DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids

Abstract

The characteristics of a biological fluid sample having an analyte are determined from a model constructed from plural known biological fluid samples. The model is a function of the concentration of materials in the known fluid samples as a function of absorption of wideband infrared energy. The wideband infrared energy is coupled to the analyte containing sample so there is differential absorption of the infrared energy as a function of the wavelength of the wideband infrared energy incident on the analyte containing sample. The differential absorption causes intensity variations of the infrared energy incident on the analyte containing sample as a function of sample wavelength of the energy, and concentration of the unknown analyte is determined from the thus-derived intensity variations of the infrared energy as a function of wavelength from the model absorption versus wavelength function.

Inventors:
 [1];  [1];  [1];  [1]
  1. Albuquerque, NM
Issue Date:
Research Org.:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
OSTI Identifier:
867627
Patent Number(s):
4975581
Assignee:
University of New Mexico (Albuquerque, NM)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC04-76
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; apparatus; determining; similarity; biological; analyte; model; constructed; fluids; characteristics; fluid; sample; determined; plural; samples; function; concentration; materials; absorption; wideband; infrared; energy; coupled; containing; differential; wavelength; incident; causes; intensity; variations; thus-derived; versus; energy incident; differential absorption; intensity variations; fluid sample; infrared energy; fluid samples; biological fluids; versus wavelength; biological fluid; model constructed; containing sample; /250/600/702/

Citation Formats

Robinson, Mark R, Ward, Kenneth J, Eaton, Robert P, and Haaland, David M. Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids. United States: N. p., 1990. Web.
Robinson, Mark R, Ward, Kenneth J, Eaton, Robert P, & Haaland, David M. Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids. United States.
Robinson, Mark R, Ward, Kenneth J, Eaton, Robert P, and Haaland, David M. Mon . "Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids". United States. https://www.osti.gov/servlets/purl/867627.
@article{osti_867627,
title = {Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids},
author = {Robinson, Mark R and Ward, Kenneth J and Eaton, Robert P and Haaland, David M},
abstractNote = {The characteristics of a biological fluid sample having an analyte are determined from a model constructed from plural known biological fluid samples. The model is a function of the concentration of materials in the known fluid samples as a function of absorption of wideband infrared energy. The wideband infrared energy is coupled to the analyte containing sample so there is differential absorption of the infrared energy as a function of the wavelength of the wideband infrared energy incident on the analyte containing sample. The differential absorption causes intensity variations of the infrared energy incident on the analyte containing sample as a function of sample wavelength of the energy, and concentration of the unknown analyte is determined from the thus-derived intensity variations of the infrared energy as a function of wavelength from the model absorption versus wavelength function.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 1990},
month = {Mon Jan 01 00:00:00 EST 1990}
}