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Title: Method of identity analyte-binding peptides

Abstract

A method for affinity chromatography or adsorption of a designated analyte utilizes a paralog as the affinity partner. The immobilized paralog can be used in purification or analysis of the analyte; the paralog can also be used as a substitute for antibody in an immunoassay. The paralog is identified by screening candidate peptide sequences of 4-20 amino acids for specific affinity to the analyte.

Inventors:
 [1]
  1. San Francisco, CA
Issue Date:
Research Org.:
Terrapin Diagnostics Ltd
OSTI Identifier:
867558
Patent Number(s):
4963263
Assignee:
Terrapin Technologies, Inc. (San Francisco, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
DOE Contract Number:  
AC03-88ER80678
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; identity; analyte-binding; peptides; affinity; chromatography; adsorption; designated; analyte; utilizes; paralog; partner; immobilized; purification; analysis; substitute; antibody; immunoassay; identified; screening; candidate; peptide; sequences; 4-20; amino; acids; specific; amino acid; amino acids; specific affinity; /210/436/530/

Citation Formats

Kauvar, Lawrence M. Method of identity analyte-binding peptides. United States: N. p., 1990. Web.
Kauvar, Lawrence M. Method of identity analyte-binding peptides. United States.
Kauvar, Lawrence M. Mon . "Method of identity analyte-binding peptides". United States. https://www.osti.gov/servlets/purl/867558.
@article{osti_867558,
title = {Method of identity analyte-binding peptides},
author = {Kauvar, Lawrence M},
abstractNote = {A method for affinity chromatography or adsorption of a designated analyte utilizes a paralog as the affinity partner. The immobilized paralog can be used in purification or analysis of the analyte; the paralog can also be used as a substitute for antibody in an immunoassay. The paralog is identified by screening candidate peptide sequences of 4-20 amino acids for specific affinity to the analyte.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1990},
month = {1}
}