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Title: Porphyrins for boron neutron capture therapy

Abstract

Novel compounds for treatment of brain tumors in Boron Neutron Capture Therapy are disclosed. A method for preparing the compounds as well as pharmaceutical compositions containing said compounds are also disclosed. The compounds are water soluble, non-toxic and non-labile boronated porphyrins which show significant uptake and retention in tumors.

Inventors:
 [1];  [2]
  1. (Center Moriches, NY)
  2. (Bremen, DE)
Issue Date:
Research Org.:
ASSOC UNIVERSITIES INC
OSTI Identifier:
867537
Patent Number(s):
4959356
Assignee:
United States of America as represented by United States (Washington, DC) BNL
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
porphyrins; boron; neutron; capture; therapy; novel; compounds; treatment; brain; tumors; disclosed; method; preparing; pharmaceutical; compositions; containing; water; soluble; non-toxic; non-labile; boronated; significant; uptake; retention; pharmaceutical compositions; water soluble; neutron capture; boron neutron; capture therapy; compositions containing; novel compounds; pharmaceutical composition; compositions contain; novel compound; brain tumors; boronated porphyrins; /424/999/

Citation Formats

Miura, Michiko, and Gabel, Detlef. Porphyrins for boron neutron capture therapy. United States: N. p., 1990. Web.
Miura, Michiko, & Gabel, Detlef. Porphyrins for boron neutron capture therapy. United States.
Miura, Michiko, and Gabel, Detlef. Mon . "Porphyrins for boron neutron capture therapy". United States. https://www.osti.gov/servlets/purl/867537.
@article{osti_867537,
title = {Porphyrins for boron neutron capture therapy},
author = {Miura, Michiko and Gabel, Detlef},
abstractNote = {Novel compounds for treatment of brain tumors in Boron Neutron Capture Therapy are disclosed. A method for preparing the compounds as well as pharmaceutical compositions containing said compounds are also disclosed. The compounds are water soluble, non-toxic and non-labile boronated porphyrins which show significant uptake and retention in tumors.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1990},
month = {1}
}

Patent:

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