Differential homogeneous immunosensor device

Malmros, Mark K

Title: Differential homogeneous immunosensor device

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Abstract

There is provided a novel method of testing for the presence of an analyte in a fluid suspected of containing the same. In this method, in the presence of the analyte, a substance capable of modifying certain characteristics of the substrate is bound to the substrate and the change in these qualities is measured. While the method may be modified for carrying out quantitative differential analyses, it eliminates the need for washing analyte from the substrate which is characteristic of prior art methods.

Inventors:

Malmros, Mark K ^[1]; Gulbinski, III, Julian ^[2]

Newton, PA
(Jamison, PA)

Issue Date:: 1990-04-10

Research Org.:: MKM Research Ohmicron

OSTI Identifier:: 867333

Patent Number(s):: 4916075

Application Number:: 07/087,087

Assignee:: Ohmicron Corporation (DE)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

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G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/5438 - {Electrodes}
G01N33/54306 - {Solid-phase reaction mechanisms}

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/817 - Enzyme or microbe electrode

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DOE Contract Number:: AC01-84ER80173

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: differential; homogeneous; immunosensor; device; provided; novel; method; testing; presence; analyte; fluid; suspected; containing; substance; capable; modifying; characteristics; substrate; bound; change; qualities; measured; modified; carrying; quantitative; analyses; eliminates; washing; characteristic; prior; methods; novel method; sensor device; /435/204/324/422/436/

Citation Formats


                    Malmros, Mark K, and Gulbinski, III, Julian. Differential homogeneous immunosensor device.  United States: N. p., 1990. 
        Web.

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                    Malmros, Mark K, & Gulbinski, III, Julian. Differential homogeneous immunosensor device.  United States.

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                    Malmros, Mark K, and Gulbinski, III, Julian. Tue .  
        "Differential homogeneous immunosensor device".  United States.  https://www.osti.gov/servlets/purl/867333.

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@article{osti_867333,

  title        = {Differential homogeneous immunosensor device},

  author       = {Malmros, Mark K and Gulbinski, III, Julian},

  abstractNote = {There is provided a novel method of testing for the presence of an analyte in a fluid suspected of containing the same. In this method, in the presence of the analyte, a substance capable of modifying certain characteristics of the substrate is bound to the substrate and the change in these qualities is measured. While the method may be modified for carrying out quantitative differential analyses, it eliminates the need for washing analyte from the substrate which is characteristic of prior art methods.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1990},

  month        = {4}

}

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