Laser particle sorter
Abstract
Method and apparatus for sorting particles, such as biological particles. A first laser defines an optical path having an intensity gradient which is effective to propel the particles along the path but which is sufficiently weak that the particles are not trapped in an axial direction. A probe laser beam interrogates the particles to identify predetermined phenotypical characteristics of the particles. A second laser beam intersects the driving first laser beam, wherein the second laser beam is activated by an output signal indicative of a predetermined characteristic. The second laser beam is switchable between a first intensity and a second intensity, where the first intensity is effective to displace selected particles from the driving laser beam and the second intensity is effective to propel selected particles along the deflection laser beam. The selected particles may then be propelled by the deflection beam to a location effective for further analysis.
- Inventors:
-
- Los Alamos, NM
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- OSTI Identifier:
- 867213
- Patent Number(s):
- 4887721
- Assignee:
- United States of America as represented by United States (Washington, DC)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B07 - SEPARATING SOLIDS FROM SOLIDS B07C - POSTAL SORTING
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- laser; particle; sorter; method; apparatus; sorting; particles; biological; defines; optical; path; intensity; gradient; effective; propel; sufficiently; weak; trapped; axial; direction; probe; beam; interrogates; identify; predetermined; phenotypical; characteristics; intersects; driving; activated; output; signal; indicative; characteristic; switchable; displace; selected; deflection; propelled; location; analysis; biological particle; laser beam; output signal; optical path; signal indicative; axial direction; selected particle; biological particles; selected particles; /209/356/
Citation Formats
Martin, John C, and Buican, Tudor N. Laser particle sorter. United States: N. p., 1989.
Web.
Martin, John C, & Buican, Tudor N. Laser particle sorter. United States.
Martin, John C, and Buican, Tudor N. Sun .
"Laser particle sorter". United States. https://www.osti.gov/servlets/purl/867213.
@article{osti_867213,
title = {Laser particle sorter},
author = {Martin, John C and Buican, Tudor N},
abstractNote = {Method and apparatus for sorting particles, such as biological particles. A first laser defines an optical path having an intensity gradient which is effective to propel the particles along the path but which is sufficiently weak that the particles are not trapped in an axial direction. A probe laser beam interrogates the particles to identify predetermined phenotypical characteristics of the particles. A second laser beam intersects the driving first laser beam, wherein the second laser beam is activated by an output signal indicative of a predetermined characteristic. The second laser beam is switchable between a first intensity and a second intensity, where the first intensity is effective to displace selected particles from the driving laser beam and the second intensity is effective to propel selected particles along the deflection laser beam. The selected particles may then be propelled by the deflection beam to a location effective for further analysis.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sun Jan 01 00:00:00 EST 1989},
month = {Sun Jan 01 00:00:00 EST 1989}
}