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Title: Laser particle sorter

Abstract

Method and apparatus for sorting particles, such as biological particles. A first laser defines an optical path having an intensity gradient which is effective to propel the particles along the path but which is sufficiently weak that the particles are not trapped in an axial direction. A probe laser beam interrogates the particles to identify predetermined phenotypical characteristics of the particles. A second laser beam intersects the driving first laser beam, wherein the second laser beam is activated by an output signal indicative of a predetermined characteristic. The second laser beam is switchable between a first intensity and a second intensity, where the first intensity is effective to displace selected particles from the driving laser beam and the second intensity is effective to propel selected particles along the deflection laser beam. The selected particles may then be propelled by the deflection beam to a location effective for further analysis.

Inventors:
 [1];  [1]
  1. (Los Alamos, NM)
Issue Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM
OSTI Identifier:
867213
Patent Number(s):
4887721
Assignee:
United States of America as represented by United States (Washington, DC) LANL
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
laser; particle; sorter; method; apparatus; sorting; particles; biological; defines; optical; path; intensity; gradient; effective; propel; sufficiently; weak; trapped; axial; direction; probe; beam; interrogates; identify; predetermined; phenotypical; characteristics; intersects; driving; activated; output; signal; indicative; characteristic; switchable; displace; selected; deflection; propelled; location; analysis; biological particle; laser beam; output signal; optical path; signal indicative; axial direction; selected particle; biological particles; selected particles; /209/356/

Citation Formats

Martin, John C., and Buican, Tudor N. Laser particle sorter. United States: N. p., 1989. Web.
Martin, John C., & Buican, Tudor N. Laser particle sorter. United States.
Martin, John C., and Buican, Tudor N. Sun . "Laser particle sorter". United States. https://www.osti.gov/servlets/purl/867213.
@article{osti_867213,
title = {Laser particle sorter},
author = {Martin, John C. and Buican, Tudor N.},
abstractNote = {Method and apparatus for sorting particles, such as biological particles. A first laser defines an optical path having an intensity gradient which is effective to propel the particles along the path but which is sufficiently weak that the particles are not trapped in an axial direction. A probe laser beam interrogates the particles to identify predetermined phenotypical characteristics of the particles. A second laser beam intersects the driving first laser beam, wherein the second laser beam is activated by an output signal indicative of a predetermined characteristic. The second laser beam is switchable between a first intensity and a second intensity, where the first intensity is effective to displace selected particles from the driving laser beam and the second intensity is effective to propel selected particles along the deflection laser beam. The selected particles may then be propelled by the deflection beam to a location effective for further analysis.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1989},
month = {1}
}

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