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Title: Biological particle identification apparatus

Abstract

An apparatus and method for making multiparameter light scattering measurements from suspensions of biological particles is described. Fourteen of the sixteen Mueller matrix elements describing the particles under investigation can be substantially individually determined as a function of scattering angle and probing radiations wavelength, eight elements simultaneously for each of two apparatus configurations using an apparatus which incluees, in its simplest form, two polarization modulators each operating at a chosen frequency, one polarizer, a source of monochromatic electromagnetic radiation, a detector sensitive to the wavelength of radiation employed, eight phase-sensitive detectors, and appropriate electronics. A database of known biological particle suspensions can be assembled, and unknown samples can be quickly identified once measurements are performed on it according to the teachings of the subject invention, and a comparison is made with the database.

Inventors:
 [1];  [1];  [1];  [1]
  1. (Los Alamos, NM)
Issue Date:
Research Org.:
Los Alamos National Laboratory (LANL), Los Alamos, NM
OSTI Identifier:
867196
Patent Number(s):
4884886
Assignee:
United States of America as represented by Department of Energy (Washington, DC) LANL
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
biological; particle; identification; apparatus; method; multiparameter; light; scattering; measurements; suspensions; particles; described; fourteen; sixteen; mueller; matrix; elements; describing; investigation; substantially; individually; determined; function; angle; probing; radiations; wavelength; eight; simultaneously; configurations; incluees; simplest; form; polarization; modulators; operating; chosen; frequency; polarizer; source; monochromatic; electromagnetic; radiation; detector; sensitive; employed; phase-sensitive; detectors; appropriate; electronics; database; assembled; samples; quickly; identified; performed; according; teachings; subject; comparison; mueller matrix; biological particle; light scattering; electromagnetic radiation; sensitive detector; biological particles; particle suspension; scattering angle; appropriate electronics; scattering measurements; monochromatic electromagnetic; particle suspensions; particle identification; simplest form; polarization modulator; matrix elements; /356/250/

Citation Formats

Salzman, Gary C., Gregg, Charles T., Grace, W. Kevin, and Hiebert, Richard D. Biological particle identification apparatus. United States: N. p., 1989. Web.
Salzman, Gary C., Gregg, Charles T., Grace, W. Kevin, & Hiebert, Richard D. Biological particle identification apparatus. United States.
Salzman, Gary C., Gregg, Charles T., Grace, W. Kevin, and Hiebert, Richard D. Sun . "Biological particle identification apparatus". United States. https://www.osti.gov/servlets/purl/867196.
@article{osti_867196,
title = {Biological particle identification apparatus},
author = {Salzman, Gary C. and Gregg, Charles T. and Grace, W. Kevin and Hiebert, Richard D.},
abstractNote = {An apparatus and method for making multiparameter light scattering measurements from suspensions of biological particles is described. Fourteen of the sixteen Mueller matrix elements describing the particles under investigation can be substantially individually determined as a function of scattering angle and probing radiations wavelength, eight elements simultaneously for each of two apparatus configurations using an apparatus which incluees, in its simplest form, two polarization modulators each operating at a chosen frequency, one polarizer, a source of monochromatic electromagnetic radiation, a detector sensitive to the wavelength of radiation employed, eight phase-sensitive detectors, and appropriate electronics. A database of known biological particle suspensions can be assembled, and unknown samples can be quickly identified once measurements are performed on it according to the teachings of the subject invention, and a comparison is made with the database.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1989},
month = {1}
}

Patent:

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