Interface for liquid chromatograph-mass spectrometer
Abstract
A moving belt interface for real-time, high-performance liquid chromatograph (HPLC)/mass spectrometer (MS) analysis which strips away the HPLC solvent as it emerges from the end of the HPLC column and leaves a residue suitable for mass-spectral analysis. The interface includes a portable, stand-alone apparatus having a plural stage vacuum station, a continuous ribbon or belt, a drive train magnetically coupled to an external drive motor, a calibrated HPLC delivery system, a heated probe tip and means located adjacent the probe tip for direct ionization of the residue on the belt. The interface is also capable of being readily adapted to fit any mass spectrometer.
- Inventors:
-
- Pleasanton, CA
- Livermore, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 867111
- Patent Number(s):
- 4867947
- Assignee:
- Sepragen Corporation (San Leandro, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- interface; liquid; chromatograph-mass; spectrometer; moving; belt; real-time; high-performance; chromatograph; hplc; mass; analysis; strips; solvent; emerges; column; leaves; residue; suitable; mass-spectral; portable; stand-alone; apparatus; plural; stage; vacuum; station; continuous; ribbon; drive; train; magnetically; coupled; external; motor; calibrated; delivery; heated; probe; tip; means; located; adjacent; direct; ionization; capable; readily; adapted; fit; performance liquid; liquid chromatograph; chromatograph-mass spectrometer; spectral analysis; probe tip; mass spectrometer; located adjacent; magnetically coupled; drive motor; drive train; means located; hplc column; /422/250/436/
Citation Formats
Andresen, Brian D, and Fought, Eric R. Interface for liquid chromatograph-mass spectrometer. United States: N. p., 1989.
Web.
Andresen, Brian D, & Fought, Eric R. Interface for liquid chromatograph-mass spectrometer. United States.
Andresen, Brian D, and Fought, Eric R. Sun .
"Interface for liquid chromatograph-mass spectrometer". United States. https://www.osti.gov/servlets/purl/867111.
@article{osti_867111,
title = {Interface for liquid chromatograph-mass spectrometer},
author = {Andresen, Brian D and Fought, Eric R},
abstractNote = {A moving belt interface for real-time, high-performance liquid chromatograph (HPLC)/mass spectrometer (MS) analysis which strips away the HPLC solvent as it emerges from the end of the HPLC column and leaves a residue suitable for mass-spectral analysis. The interface includes a portable, stand-alone apparatus having a plural stage vacuum station, a continuous ribbon or belt, a drive train magnetically coupled to an external drive motor, a calibrated HPLC delivery system, a heated probe tip and means located adjacent the probe tip for direct ionization of the residue on the belt. The interface is also capable of being readily adapted to fit any mass spectrometer.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sun Jan 01 00:00:00 EST 1989},
month = {Sun Jan 01 00:00:00 EST 1989}
}
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