Astatinated organic compounds

Milius, Richard A; Lambrecht, Richard M; Bloomer, William D

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Title: Astatinated organic compounds

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Abstract

Methods and kits for incorporating a radioactive astatine isotope (particularly .sup.211 At) into an organic compound by electrophilic astatodestannylation of organostannanes.

Inventors:

Milius, Richard A ^[1]; Lambrecht, Richard M ^[2]; Bloomer, William D ^[3]

Boston, MA
Quogue, NY
Wilton, CT

Issue Date:: 1989-05-02

Research Org.:: Associated Universities, Inc., Upton, NY (United States)

OSTI Identifier:: 866937

Patent Number(s):: 4826672

Application Number:: 06/742,206

Assignee:: President and Fellows of Harvard College (Cambridge, MA)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K2121/00 - Preparations for use in therapy
A61K51/0406 - {Amines, polyamines, e.g. spermine, spermidine, amino acids,
A61K51/0491 - {Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers}
A61K51/1093 - {conjugates with carriers being antibodies}

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C217/20 - by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/60 - involving radioactive labelled substances

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DOE Contract Number:: AC02-76CH00016

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: astatinated; organic; compounds; methods; kits; incorporating; radioactive; astatine; isotope; particularly; 211; compound; electrophilic; astatodestannylation; organostannanes; organic compound; organic compounds; /530/999/

Citation Formats


                    Milius, Richard A, Lambrecht, Richard M, and Bloomer, William D. Astatinated organic compounds.  United States: N. p., 1989. 
        Web.

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                    Milius, Richard A, Lambrecht, Richard M, & Bloomer, William D. Astatinated organic compounds.  United States.

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                    Milius, Richard A, Lambrecht, Richard M, and Bloomer, William D. Tue .  
        "Astatinated organic compounds".  United States.  https://www.osti.gov/servlets/purl/866937.

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@article{osti_866937,

  title        = {Astatinated organic compounds},

  author       = {Milius, Richard A and Lambrecht, Richard M and Bloomer, William D},

  abstractNote = {Methods and kits for incorporating a radioactive astatine isotope (particularly .sup.211 At) into an organic compound by electrophilic astatodestannylation of organostannanes.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1989},

  month        = {5}

}

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