Cell lines for the production of monoclonal antibodies to human glycophorin A
Abstract
Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.
- Inventors:
-
- Livermore, CA
- Del Mar, CA
- San Ramon, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 866704
- Patent Number(s):
- 4767710
- Assignee:
- United States of America as represented by United States (Washington, DC)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- cell; lines; production; monoclonal; antibodies; human; glycophorin; cloned; mouse; hybridoma; established; continuously; produce; differentiate; forms; potential; application; blood; reagents; markers; terminally; differentiated; erythroid; cells; immunofluorescent; labels; somatically; variant; erythrocytes; cell lines; monoclonal antibodies; fluorescent labels; human blood; human glycophorin; cell line; cloned mouse; mouse hybridoma; continuously produce; hybridoma cell; produce antibodies; /435/530/
Citation Formats
Bigbee, William L, Fong, Stella S. N., Jensen, Ronald H, Vanderlaan, Martin, and Langlois, Richard G. Cell lines for the production of monoclonal antibodies to human glycophorin A. United States: N. p., 1988.
Web.
Bigbee, William L, Fong, Stella S. N., Jensen, Ronald H, Vanderlaan, Martin, & Langlois, Richard G. Cell lines for the production of monoclonal antibodies to human glycophorin A. United States.
Bigbee, William L, Fong, Stella S. N., Jensen, Ronald H, Vanderlaan, Martin, and Langlois, Richard G. Fri .
"Cell lines for the production of monoclonal antibodies to human glycophorin A". United States. https://www.osti.gov/servlets/purl/866704.
@article{osti_866704,
title = {Cell lines for the production of monoclonal antibodies to human glycophorin A},
author = {Bigbee, William L and Fong, Stella S. N. and Jensen, Ronald H and Vanderlaan, Martin and Langlois, Richard G},
abstractNote = {Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Jan 01 00:00:00 EST 1988},
month = {Fri Jan 01 00:00:00 EST 1988}
}
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