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Title: Radiolabeled dimethyl branched long chain fatty acid for heart imaging

Abstract

A radiolabeled long chain fatty acid for heart imaging that has dimethyl branching at one of the carbons of the chain which inhibits the extent to which oxidation can occur. The closer to the carboxyl the branching is positioned, the more limited the oxidation, thereby resulting in prolonged retention of the radiolabeled compound in the heart.

Inventors:
 [1];  [2];  [3]
  1. (Oak Ridge, TN)
  2. Knoxville, TN
  3. Woippy, FR
Issue Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
OSTI Identifier:
866686
Patent Number(s):
4764358
Application Number:
06/868,480
Assignee:
United States of America as represented by United States (Washington, DC)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
radiolabeled; dimethyl; branched; chain; fatty; acid; heart; imaging; branching; carbons; inhibits; extent; oxidation; occur; closer; carboxyl; positioned; limited; resulting; prolonged; retention; compound; fatty acid; prolonged retention; chain fatty; heart imaging; radiolabeled compound; /424/999/

Citation Formats

Knapp, Jr., Furn F., Goodman, Mark M, and Kirsch, Gilbert. Radiolabeled dimethyl branched long chain fatty acid for heart imaging. United States: N. p., 1988. Web.
Knapp, Jr., Furn F., Goodman, Mark M, & Kirsch, Gilbert. Radiolabeled dimethyl branched long chain fatty acid for heart imaging. United States.
Knapp, Jr., Furn F., Goodman, Mark M, and Kirsch, Gilbert. Tue . "Radiolabeled dimethyl branched long chain fatty acid for heart imaging". United States. https://www.osti.gov/servlets/purl/866686.
@article{osti_866686,
title = {Radiolabeled dimethyl branched long chain fatty acid for heart imaging},
author = {Knapp, Jr., Furn F. and Goodman, Mark M and Kirsch, Gilbert},
abstractNote = {A radiolabeled long chain fatty acid for heart imaging that has dimethyl branching at one of the carbons of the chain which inhibits the extent to which oxidation can occur. The closer to the carboxyl the branching is positioned, the more limited the oxidation, thereby resulting in prolonged retention of the radiolabeled compound in the heart.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1988},
month = {8}
}

Patent:

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