Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands
Abstract
A bisamide-bisthiol ligand containing fatty acid substituted thiol useful for producing Tc-labelled radiodiagnostic imaging agents is described. The ligand forms a complex with the radionuclide .sup.99m Tc suitable for administration as a radiopharmaceutical to obtain images of the heart for diagnosis of myocardial disfunction.
- Inventors:
-
- Newton Centre, MA
- Wellesley, MA
- Needham, MA
- Issue Date:
- Research Org.:
- Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
- OSTI Identifier:
- 866599
- Patent Number(s):
- 4746505
- Application Number:
- 06/727,582
- Assignee:
- President and Fellows of Harvard College (Cambridge, MA); Children's Medical Center Corp. (Boston, MA); Massachusetts Institute of Technology (Cambridge, MA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07F - ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- DOE Contract Number:
- AC02-76EV04115
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- technetium; radiodiagnostic; fatty; acids; derived; bisamide; bisthiol; ligands; bisamide-bisthiol; ligand; containing; acid; substituted; thiol; useful; producing; tc-labelled; imaging; agents; described; forms; complex; radionuclide; 99m; tc; suitable; administration; radiopharmaceutical; obtain; images; heart; diagnosis; myocardial; disfunction; fatty acids; imaging agents; fatty acid; imaging agent; diagnostic imaging; technetium radiodiagnostic; tc-labelled radiodiagnostic; producing tc-labelled; acid substituted; bisamide bisthiol; ligand forms; /424/422/999/
Citation Formats
Jones, Alun G, Lister-James, John, and Davison, Alan. Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands. United States: N. p., 1988.
Web.
Jones, Alun G, Lister-James, John, & Davison, Alan. Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands. United States.
Jones, Alun G, Lister-James, John, and Davison, Alan. Tue .
"Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands". United States. https://www.osti.gov/servlets/purl/866599.
@article{osti_866599,
title = {Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands},
author = {Jones, Alun G and Lister-James, John and Davison, Alan},
abstractNote = {A bisamide-bisthiol ligand containing fatty acid substituted thiol useful for producing Tc-labelled radiodiagnostic imaging agents is described. The ligand forms a complex with the radionuclide .sup.99m Tc suitable for administration as a radiopharmaceutical to obtain images of the heart for diagnosis of myocardial disfunction.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1988},
month = {5}
}