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Title: Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands

Abstract

A bisamide-bisthiol ligand containing fatty acid substituted thiol useful for producing Tc-labelled radiodiagnostic imaging agents is described. The ligand forms a complex with the radionuclide .sup.99m Tc suitable for administration as a radiopharmaceutical to obtain images of the heart for diagnosis of myocardial disfunction.

Inventors:
 [1];  [2];  [3]
+ Show Inventor Affiliations
  1. Newton Centre, MA
  2. Wellesley, MA
  3. Needham, MA
Issue Date:
Research Org.:
Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
OSTI Identifier:
866599
Patent Number(s):
4746505
Application Number:
06/727,582
Assignee:
President and Fellows of Harvard College (Cambridge, MA); Children's Medical Center Corp. (Boston, MA); Massachusetts Institute of Technology (Cambridge, MA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07F - ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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DOE Contract Number:  
AC02-76EV04115
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
technetium; radiodiagnostic; fatty; acids; derived; bisamide; bisthiol; ligands; bisamide-bisthiol; ligand; containing; acid; substituted; thiol; useful; producing; tc-labelled; imaging; agents; described; forms; complex; radionuclide; 99m; tc; suitable; administration; radiopharmaceutical; obtain; images; heart; diagnosis; myocardial; disfunction; fatty acids; imaging agents; fatty acid; imaging agent; diagnostic imaging; technetium radiodiagnostic; tc-labelled radiodiagnostic; producing tc-labelled; acid substituted; bisamide bisthiol; ligand forms; /424/422/999/

Citation Formats

Jones, Alun G, Lister-James, John, and Davison, Alan. Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands. United States: N. p., 1988. Web.
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Jones, Alun G, Lister-James, John, & Davison, Alan. Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands. United States.
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Jones, Alun G, Lister-James, John, and Davison, Alan. Tue . "Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands". United States. https://www.osti.gov/servlets/purl/866599.
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@article{osti_866599,
title = {Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands},
author = {Jones, Alun G and Lister-James, John and Davison, Alan},
abstractNote = {A bisamide-bisthiol ligand containing fatty acid substituted thiol useful for producing Tc-labelled radiodiagnostic imaging agents is described. The ligand forms a complex with the radionuclide .sup.99m Tc suitable for administration as a radiopharmaceutical to obtain images of the heart for diagnosis of myocardial disfunction.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1988},
month = {5}
}
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