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Title: Radioiodinated maleimides and use as agents for radiolabeling antibodies

Abstract

A radiopharmaceutical for antibody labeling comprising an iodophenyl maleimide that attaches thiol sites of proteins thereby maintaining bioreactivity largely located at the nitrogen sites.

Inventors:
 [1]
  1. (Oak Ridge, TN)
Issue Date:
Research Org.:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN
OSTI Identifier:
866558
Patent Number(s):
4735792
Assignee:
United States of America as represented by United States (Washington, DC) ORNL
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
radioiodinated; maleimides; agents; radiolabeling; antibodies; radiopharmaceutical; antibody; labeling; comprising; iodophenyl; maleimide; attaches; thiol; sites; proteins; maintaining; bioreactivity; located; nitrogen; radiolabeling antibodies; antibody labeling; nitrogen sites; /424/999/

Citation Formats

Srivastava, Prem C. Radioiodinated maleimides and use as agents for radiolabeling antibodies. United States: N. p., 1988. Web.
Srivastava, Prem C. Radioiodinated maleimides and use as agents for radiolabeling antibodies. United States.
Srivastava, Prem C. Fri . "Radioiodinated maleimides and use as agents for radiolabeling antibodies". United States. https://www.osti.gov/servlets/purl/866558.
@article{osti_866558,
title = {Radioiodinated maleimides and use as agents for radiolabeling antibodies},
author = {Srivastava, Prem C.},
abstractNote = {A radiopharmaceutical for antibody labeling comprising an iodophenyl maleimide that attaches thiol sites of proteins thereby maintaining bioreactivity largely located at the nitrogen sites.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1988},
month = {1}
}

Patent:

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