Rapid brain scanning radiopharmaceutical
Abstract
A method for detecting the blood flow in animals, particularly in the brain, is provided wherein a detectable amount of a novel radioactive compound of the formula I is administered to one animal: ##STR1## wherein R.sub.1 and R.sub.2 are independently alkyl of 1 to 6 carbon atoms or benzyl; R.sub.3 is alkyl of 1 to 6 carbon atoms, benzyl, cyclopropylalkyl of 4 to 6 carbon atoms, or cyanoalkyl of 2 to 6 carbon atoms; R.sub.4 is hydrogen, benzyl or alkyl of 1 to 6 carbon atoms; with the provisos that R.sub.4 is not isopropyl and when R.sub.4 is methyl, R.sub.3 is not benzyl; and X is a radioactive halogen.
- Inventors:
-
- (Berkeley, CA)
- Lafayette, CA
- Oakland, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 866163
- Patent Number(s):
- 4647446
- Assignee:
- Regents of University of California (Berkeley, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- rapid; brain; scanning; radiopharmaceutical; method; detecting; blood; flow; animals; particularly; provided; detectable; amount; novel; radioactive; compound; formula; administered; animal; str1; independently; alkyl; carbon; atoms; benzyl; cyclopropylalkyl; cyanoalkyl; hydrogen; provisos; isopropyl; methyl; halogen; blood flow; carbon atoms; carbon atom; radioactive compound; active compound; rapid brain; novel radioactive; detectable amount; /424/999/
Citation Formats
Sargent, III, Thornton W., Shulgin, Alexander T, and Mathis, Chester A. Rapid brain scanning radiopharmaceutical. United States: N. p., 1987.
Web.
Sargent, III, Thornton W., Shulgin, Alexander T, & Mathis, Chester A. Rapid brain scanning radiopharmaceutical. United States.
Sargent, III, Thornton W., Shulgin, Alexander T, and Mathis, Chester A. Thu .
"Rapid brain scanning radiopharmaceutical". United States. https://www.osti.gov/servlets/purl/866163.
@article{osti_866163,
title = {Rapid brain scanning radiopharmaceutical},
author = {Sargent, III, Thornton W. and Shulgin, Alexander T and Mathis, Chester A},
abstractNote = {A method for detecting the blood flow in animals, particularly in the brain, is provided wherein a detectable amount of a novel radioactive compound of the formula I is administered to one animal: ##STR1## wherein R.sub.1 and R.sub.2 are independently alkyl of 1 to 6 carbon atoms or benzyl; R.sub.3 is alkyl of 1 to 6 carbon atoms, benzyl, cyclopropylalkyl of 4 to 6 carbon atoms, or cyanoalkyl of 2 to 6 carbon atoms; R.sub.4 is hydrogen, benzyl or alkyl of 1 to 6 carbon atoms; with the provisos that R.sub.4 is not isopropyl and when R.sub.4 is methyl, R.sub.3 is not benzyl; and X is a radioactive halogen.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1987},
month = {1}
}
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