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Title: Lipoprotein marker for hypertriglyceridemia

Abstract

Methods and compositions are provided for the detection of a particular low density lipoprotein which has been found to be a marker for patients suffering from type IV hypertriglyceridemia. A monoclonal antibody capable of specifically binding to a characteristic epitopic site on this LDL subspecies can be utilized in a wide variety of immunoassays. Hybridoma cell line SPL.IVA5A1 was deposited at the American Type Culture Collection on Mar. 29, 1984, and granted accession no. HB 8535.

Inventors:
 [1];  [2];  [3]
+ Show Inventor Affiliations
  1. El Cerrito, CA
  2. Kensington, CA
  3. Berkeley, CA
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
OSTI Identifier:
866035
Patent Number(s):
4619895
Assignee:
Regents of University of California (Berkeley, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
lipoprotein; marker; hypertriglyceridemia; methods; compositions; provided; detection; particular; density; found; patients; suffering; type; monoclonal; antibody; capable; specifically; binding; characteristic; epitopic; site; ldl; subspecies; utilized; wide; variety; immunoassays; hybridoma; cell; line; spl; iva5a1; deposited; american; culture; collection; 29; 1984; granted; accession; hb; 8535; monoclonal antibody; wide variety; specifically bind; cell line; type culture; hybridoma cell; american type; density lipoprotein; culture collection; /435/436/530/

Citation Formats

Cubicciotti, Roger S, Karu, Alexander E, and Krauss, Ronald M. Lipoprotein marker for hypertriglyceridemia. United States: N. p., 1986. Web.
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Cubicciotti, Roger S, Karu, Alexander E, & Krauss, Ronald M. Lipoprotein marker for hypertriglyceridemia. United States.
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Cubicciotti, Roger S, Karu, Alexander E, and Krauss, Ronald M. Wed . "Lipoprotein marker for hypertriglyceridemia". United States. https://www.osti.gov/servlets/purl/866035.
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@article{osti_866035,
title = {Lipoprotein marker for hypertriglyceridemia},
author = {Cubicciotti, Roger S and Karu, Alexander E and Krauss, Ronald M},
abstractNote = {Methods and compositions are provided for the detection of a particular low density lipoprotein which has been found to be a marker for patients suffering from type IV hypertriglyceridemia. A monoclonal antibody capable of specifically binding to a characteristic epitopic site on this LDL subspecies can be utilized in a wide variety of immunoassays. Hybridoma cell line SPL.IVA5A1 was deposited at the American Type Culture Collection on Mar. 29, 1984, and granted accession no. HB 8535.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1986},
month = {Wed Jan 01 00:00:00 EST 1986}
}
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