Antihypertensive neutral lipid
Abstract
The invention relates to the discovery of a class of neutral acetylated ether-linked glycerolipids having the capacity to lower blood pressure in warm-blooded animals. This physiological effect is structure sensitive requiring a long chain alkyl group at the sn-1 position and a short carbon chain acyl group (acetyl or propionyl) at the sn-2 position, and a hydroxyl group at the sn-3 position.
- Inventors:
-
- Oak Ridge, TN
- Issue Date:
- Research Org.:
- Oak Ridge Associated Universities (ORAU), Oak Ridge, TN (United States)
- OSTI Identifier:
- 865882
- Patent Number(s):
- 4595681
- Assignee:
- United States of America as represented by United States (Washington, DC)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- AC05-76OR00033
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- antihypertensive; neutral; lipid; relates; discovery; acetylated; ether-linked; glycerolipids; capacity; blood; pressure; warm-blooded; animals; physiological; effect; structure; sensitive; requiring; chain; alkyl; sn-1; position; carbon; acyl; acetyl; propionyl; sn-2; hydroxyl; sn-3; chain alkyl; warm-blooded animals; carbon chain; blood pressure; /514/999/
Citation Formats
Snyder, Fred L, and Blank, Merle L. Antihypertensive neutral lipid. United States: N. p., 1986.
Web.
Snyder, Fred L, & Blank, Merle L. Antihypertensive neutral lipid. United States.
Snyder, Fred L, and Blank, Merle L. Wed .
"Antihypertensive neutral lipid". United States. https://www.osti.gov/servlets/purl/865882.
@article{osti_865882,
title = {Antihypertensive neutral lipid},
author = {Snyder, Fred L and Blank, Merle L},
abstractNote = {The invention relates to the discovery of a class of neutral acetylated ether-linked glycerolipids having the capacity to lower blood pressure in warm-blooded animals. This physiological effect is structure sensitive requiring a long chain alkyl group at the sn-1 position and a short carbon chain acyl group (acetyl or propionyl) at the sn-2 position, and a hydroxyl group at the sn-3 position.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1986},
month = {Wed Jan 01 00:00:00 EST 1986}
}
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