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Title: Antihypertensive neutral lipid

Abstract

The invention relates to the discovery of a class of neutral acetylated ether-linked glycerolipids having the capacity to lower blood pressure in warm-blooded animals. This physiological effect is structure sensitive requiring a long chain alkyl group at the sn-1 position and a short carbon chain acyl group (acetyl or propionyl) at the sn-2 position, and a hydroxyl group at the sn-3 position.

Inventors:
 [1];  [1]
  1. Oak Ridge, TN
Issue Date:
Research Org.:
OAK RIDGE ASSOC UNIV
OSTI Identifier:
865882
Patent Number(s):
4595681
Assignee:
United States of America as represented by United States (Washington, DC)
DOE Contract Number:  
AC05-76OR00033
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
antihypertensive; neutral; lipid; relates; discovery; acetylated; ether-linked; glycerolipids; capacity; blood; pressure; warm-blooded; animals; physiological; effect; structure; sensitive; requiring; chain; alkyl; sn-1; position; carbon; acyl; acetyl; propionyl; sn-2; hydroxyl; sn-3; chain alkyl; warm-blooded animals; carbon chain; blood pressure; /514/999/

Citation Formats

Snyder, Fred L, and Blank, Merle L. Antihypertensive neutral lipid. United States: N. p., 1986. Web.
Snyder, Fred L, & Blank, Merle L. Antihypertensive neutral lipid. United States.
Snyder, Fred L, and Blank, Merle L. Wed . "Antihypertensive neutral lipid". United States. https://www.osti.gov/servlets/purl/865882.
@article{osti_865882,
title = {Antihypertensive neutral lipid},
author = {Snyder, Fred L and Blank, Merle L},
abstractNote = {The invention relates to the discovery of a class of neutral acetylated ether-linked glycerolipids having the capacity to lower blood pressure in warm-blooded animals. This physiological effect is structure sensitive requiring a long chain alkyl group at the sn-1 position and a short carbon chain acyl group (acetyl or propionyl) at the sn-2 position, and a hydroxyl group at the sn-3 position.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1986},
month = {1}
}

Patent:

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