Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid
Abstract
A nonmitogenic angiogenesis factor is isolated from wound fluid by dialysis to include materials in the molecular size range of 2,000 to 14,000, lyophilization, and chromatography. The nonmitogenic angiogenesis factor is identified by activity by corneal implant assay and by cell migration assay. The angiogenesis factor is also characterized by inactivity by mitogenesis assay.
- Inventors:
-
- San Francisco, CA
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 865365
- Patent Number(s):
- 4503038
- Assignee:
- Regents of University of California (Berkeley, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- AC03-76SF01012
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- extracellular; nonmitogenic; angiogenesis; factor; method; isolation; wound; fluid; isolated; dialysis; materials; molecular; size; range; 000; 14; lyophilization; chromatography; identified; activity; corneal; implant; assay; cell; migration; characterized; inactivity; mitogenesis; size range; nonmitogenic angiogenesis; cell migration; angiogenesis factor; wound fluid; /424/514/
Citation Formats
Banda, Michael J, Werb, Zena, Knighton, David R, and Hunt, Thomas K. Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid. United States: N. p., 1985.
Web.
Banda, Michael J, Werb, Zena, Knighton, David R, & Hunt, Thomas K. Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid. United States.
Banda, Michael J, Werb, Zena, Knighton, David R, and Hunt, Thomas K. Tue .
"Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid". United States. https://www.osti.gov/servlets/purl/865365.
@article{osti_865365,
title = {Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid},
author = {Banda, Michael J and Werb, Zena and Knighton, David R and Hunt, Thomas K},
abstractNote = {A nonmitogenic angiogenesis factor is isolated from wound fluid by dialysis to include materials in the molecular size range of 2,000 to 14,000, lyophilization, and chromatography. The nonmitogenic angiogenesis factor is identified by activity by corneal implant assay and by cell migration assay. The angiogenesis factor is also characterized by inactivity by mitogenesis assay.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1985},
month = {1}
}
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