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Title: Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid

Abstract

A nonmitogenic angiogenesis factor is isolated from wound fluid by dialysis to include materials in the molecular size range of 2,000 to 14,000, lyophilization, and chromatography. The nonmitogenic angiogenesis factor is identified by activity by corneal implant assay and by cell migration assay. The angiogenesis factor is also characterized by inactivity by mitogenesis assay.

Inventors:
 [1];  [1];  [1];  [1]
  1. (San Francisco, CA)
Issue Date:
Research Org.:
University of California
Sponsoring Org.:
USDOE
OSTI Identifier:
865365
Patent Number(s):
4503038
Assignee:
Regents of University of California (Berkeley, CA) OAK
DOE Contract Number:  
AC03-76SF01012
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
extracellular; nonmitogenic; angiogenesis; factor; method; isolation; wound; fluid; isolated; dialysis; materials; molecular; size; range; 000; 14; lyophilization; chromatography; identified; activity; corneal; implant; assay; cell; migration; characterized; inactivity; mitogenesis; size range; nonmitogenic angiogenesis; cell migration; angiogenesis factor; wound fluid; /424/514/

Citation Formats

Banda, Michael J., Werb, Zena, Knighton, David R., and Hunt, Thomas K. Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid. United States: N. p., 1985. Web.
Banda, Michael J., Werb, Zena, Knighton, David R., & Hunt, Thomas K. Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid. United States.
Banda, Michael J., Werb, Zena, Knighton, David R., and Hunt, Thomas K. Tue . "Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid". United States. https://www.osti.gov/servlets/purl/865365.
@article{osti_865365,
title = {Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid},
author = {Banda, Michael J. and Werb, Zena and Knighton, David R. and Hunt, Thomas K.},
abstractNote = {A nonmitogenic angiogenesis factor is isolated from wound fluid by dialysis to include materials in the molecular size range of 2,000 to 14,000, lyophilization, and chromatography. The nonmitogenic angiogenesis factor is identified by activity by corneal implant assay and by cell migration assay. The angiogenesis factor is also characterized by inactivity by mitogenesis assay.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1985},
month = {1}
}

Patent:

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