Isonitrile radionuclide complexes for labelling and imaging agents
Abstract
A coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta, is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.
- Inventors:
- Issue Date:
- Research Org.:
- Harvard Univ., Cambridge, MA (United States); Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 865034
- Patent Number(s):
- 4452774
- Application Number:
- 06/373,511
- Assignee:
- President and Fellows of Harvard College (Cambridge, MA); Massachusetts Institute of Technology (Cambridge, MA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
- DOE Contract Number:
- AC02-76EV04115
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 1982 Apr 30
- Country of Publication:
- United States
- Language:
- English
- Subject:
- isonitrile; radionuclide; complexes; labelling; imaging; agents; coordination; complex; ligand; tc; ru; mn; pd; nb; useful; diagnostic; agent; liposomes; vesicles; selected; living; cells; containing; lipid; membranes; blood; clots; myocardial; tissue; gall; bladder; etc; radionuclide complexes; living cells; isonitrile ligand; imaging agents; cells containing; isonitrile radionuclide; coordination complex; imaging agent; myocardial tissue; lipid membranes; cells contain; diagnostic agent; /424/999/987/
Citation Formats
Jones, Alun G., Davison, Alan, and Abrams, Michael J. Isonitrile radionuclide complexes for labelling and imaging agents. United States: N. p., 1984.
Web.
Jones, Alun G., Davison, Alan, & Abrams, Michael J. Isonitrile radionuclide complexes for labelling and imaging agents. United States.
Jones, Alun G., Davison, Alan, and Abrams, Michael J. Mon .
"Isonitrile radionuclide complexes for labelling and imaging agents". United States. https://www.osti.gov/servlets/purl/865034.
@article{osti_865034,
title = {Isonitrile radionuclide complexes for labelling and imaging agents},
author = {Jones, Alun G. and Davison, Alan and Abrams, Michael J.},
abstractNote = {A coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta, is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1984},
month = {6}
}
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