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Title: Isonitrile radionuclide complexes for labelling and imaging agents

Abstract

A coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta, is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.

Inventors:
 [1];  [2];  [3]
  1. Newton Centre, MA
  2. Needham, MA
  3. Allston, MA
Issue Date:
Research Org.:
Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
OSTI Identifier:
865034
Patent Number(s):
4452774
Application Number:
06/373,511
Assignee:
President and Fellows of Harvard College (Cambridge, MA); Massachusetts Institute of Technology (Cambridge, MA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07F - ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
DOE Contract Number:  
AC02-76EV04115
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
isonitrile; radionuclide; complexes; labelling; imaging; agents; coordination; complex; ligand; tc; ru; mn; pd; nb; useful; diagnostic; agent; liposomes; vesicles; selected; living; cells; containing; lipid; membranes; blood; clots; myocardial; tissue; gall; bladder; etc; radionuclide complexes; living cells; isonitrile ligand; imaging agents; cells containing; isonitrile radionuclide; coordination complex; imaging agent; myocardial tissue; lipid membranes; cells contain; diagnostic agent; /424/999/987/

Citation Formats

Jones, Alun G, Davison, Alan, and Abrams, Michael J. Isonitrile radionuclide complexes for labelling and imaging agents. United States: N. p., 1984. Web.
Jones, Alun G, Davison, Alan, & Abrams, Michael J. Isonitrile radionuclide complexes for labelling and imaging agents. United States.
Jones, Alun G, Davison, Alan, and Abrams, Michael J. Mon . "Isonitrile radionuclide complexes for labelling and imaging agents". United States. https://www.osti.gov/servlets/purl/865034.
@article{osti_865034,
title = {Isonitrile radionuclide complexes for labelling and imaging agents},
author = {Jones, Alun G and Davison, Alan and Abrams, Michael J},
abstractNote = {A coordination complex of an isonitrile ligand and radionuclide such as Tc, Ru, Co, Pt, Fe, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Pd, Nb and Ta, is useful as a diagnostic agent for labelling liposomes or vesicles, and selected living cells containing lipid membranes, such as blood clots, myocardial tissue, gall bladder tissue, etc.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1984},
month = {6}
}

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