Bioluminescence methods for enzymatic determinations

Bostick, William D; Denton, Mark S; Dinsmore, Stanley R

Title: Bioluminescence methods for enzymatic determinations

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Abstract

An enzymatic method for continuous, on-line and rapid detection of diagnostically useful biomarkers, which are symptomatic of disease or trauma-related tissue damage, is disclosed. The method is characterized by operability on authentic samples of complex biological fluids which contain the biomarkers.

Inventors:

Bostick, William D ^[1]; Denton, Mark S ^[2]; Dinsmore, Stanley R ^[3]

Oak Ridge, TN
Clinton, TN
Norris, TN

Issue Date:: 1982-01-01

Research Org.:: Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

OSTI Identifier:: 864379

Patent Number(s):: 4357420

Assignee:: United States of America as represented by United States (Washington, DC)

Patent Classifications (CPCs):: C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

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C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
C12Q1/66 - involving luciferase

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
Y10S435/808 - Optical sensing apparatus

C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
C12Q1/50 - involving creatine phosphokinase
C12Q1/32 - involving dehydrogenase

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Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: bioluminescence; methods; enzymatic; determinations; method; continuous; on-line; rapid; detection; diagnostically; useful; biomarkers; symptomatic; disease; trauma-related; tissue; damage; disclosed; characterized; operability; authentic; samples; complex; biological; fluids; contain; rapid detection; tissue damage; biological fluids; biological fluid; enzymatic method; diagnostically useful; /435/422/

Citation Formats


                    Bostick, William D, Denton, Mark S, and Dinsmore, Stanley R. Bioluminescence methods for enzymatic determinations.  United States: N. p., 1982. 
        Web.

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                    Bostick, William D, Denton, Mark S, & Dinsmore, Stanley R. Bioluminescence methods for enzymatic determinations.  United States.

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                    Bostick, William D, Denton, Mark S, and Dinsmore, Stanley R. Fri .  
        "Bioluminescence methods for enzymatic determinations".  United States.  https://www.osti.gov/servlets/purl/864379.

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@article{osti_864379,

  title        = {Bioluminescence methods for enzymatic determinations},

  author       = {Bostick, William D and Denton, Mark S and Dinsmore, Stanley R},

  abstractNote = {An enzymatic method for continuous, on-line and rapid detection of diagnostically useful biomarkers, which are symptomatic of disease or trauma-related tissue damage, is disclosed. The method is characterized by operability on authentic samples of complex biological fluids which contain the biomarkers.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1982},

  month        = {1}

}

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