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Title: Generator for ionic gallium-68 based on column chromatography

Abstract

A physiologically acceptable solution of gallium-68 fluorides, having an activity of 0.1 to 50 millicuries per milliliter of solution is provided. The solution is obtained from a generator comprising germanium-68 hexafluoride bound to a column of an anion exchange resin which forms gallium-68 in situ by eluting the column with an acid solution to form a solution containing .sup.68 Ga-fluorides. The solution then is neutralized prior to administration.

Inventors:
 [1];  [2]
  1. (Medfield, MA)
  2. (Westwood, MA)
Issue Date:
OSTI Identifier:
863980
Patent Number(s):
4288424
Assignee:
Massachusetts Institute of Technology (Cambridge, MA) OSTI
DOE Contract Number:  
E(11-1)-4115
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
generator; ionic; gallium-68; based; column; chromatography; physiologically; acceptable; solution; fluorides; activity; 50; millicuries; milliliter; provided; obtained; comprising; germanium-68; hexafluoride; bound; anion; exchange; resin; forms; situ; eluting; acid; form; containing; 68; ga-fluorides; neutralized; prior; administration; anion exchange; acid solution; solution containing; exchange resin; acceptable solution; column chromatography; physiologically acceptable; generator comprising; /424/250/376/422/521/976/

Citation Formats

Neirinckx, Rudi D., and Davis, Michael A. Generator for ionic gallium-68 based on column chromatography. United States: N. p., 1981. Web.
Neirinckx, Rudi D., & Davis, Michael A. Generator for ionic gallium-68 based on column chromatography. United States.
Neirinckx, Rudi D., and Davis, Michael A. Thu . "Generator for ionic gallium-68 based on column chromatography". United States. https://www.osti.gov/servlets/purl/863980.
@article{osti_863980,
title = {Generator for ionic gallium-68 based on column chromatography},
author = {Neirinckx, Rudi D. and Davis, Michael A.},
abstractNote = {A physiologically acceptable solution of gallium-68 fluorides, having an activity of 0.1 to 50 millicuries per milliliter of solution is provided. The solution is obtained from a generator comprising germanium-68 hexafluoride bound to a column of an anion exchange resin which forms gallium-68 in situ by eluting the column with an acid solution to form a solution containing .sup.68 Ga-fluorides. The solution then is neutralized prior to administration.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1981},
month = {1}
}

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