Generator for gallium-68 and compositions obtained therefrom
Abstract
A generator for obtaining radioactive gallium-68 from germanium-68 bound in a resin containing unsubstituted phenolic hydroxyl groups. The germanium-68 is loaded into the resin from an aqueous solution of the germanium-68. A physiologically acceptable solution of gallium-68 having an activity of 0.1 to 50 millicuries per milliliter of gallium-68 solution is obtained. The solution is obtained from the bound germanium-68 which forms gallium-68 in situ by eluting the column with a hydrochloric acid solution to form an acidic solution of gallium-68. The acidic solution of gallium-68 can be neutralized.
- Inventors:
-
- Medfield, MA
- Westwood, MA
- Issue Date:
- OSTI Identifier:
- 863870
- Patent Number(s):
- 4264468
- Assignee:
- Massachusetts Institute of Technology (Cambridge, MA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
- DOE Contract Number:
- E(11-1)-4115
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- generator; gallium-68; compositions; obtained; therefrom; obtaining; radioactive; germanium-68; bound; resin; containing; unsubstituted; phenolic; hydroxyl; loaded; aqueous; solution; physiologically; acceptable; activity; 50; millicuries; milliliter; forms; situ; eluting; column; hydrochloric; acid; form; acidic; neutralized; resin containing; phenolic hydroxyl; hydrochloric acid; acid solution; aqueous solution; acidic solution; acceptable solution; physiologically acceptable; /424/250/376/422/423/976/
Citation Formats
Neirinckx, Rudi D, and Davis, Michael A. Generator for gallium-68 and compositions obtained therefrom. United States: N. p., 1981.
Web.
Neirinckx, Rudi D, & Davis, Michael A. Generator for gallium-68 and compositions obtained therefrom. United States.
Neirinckx, Rudi D, and Davis, Michael A. Thu .
"Generator for gallium-68 and compositions obtained therefrom". United States. https://www.osti.gov/servlets/purl/863870.
@article{osti_863870,
title = {Generator for gallium-68 and compositions obtained therefrom},
author = {Neirinckx, Rudi D and Davis, Michael A},
abstractNote = {A generator for obtaining radioactive gallium-68 from germanium-68 bound in a resin containing unsubstituted phenolic hydroxyl groups. The germanium-68 is loaded into the resin from an aqueous solution of the germanium-68. A physiologically acceptable solution of gallium-68 having an activity of 0.1 to 50 millicuries per milliliter of gallium-68 solution is obtained. The solution is obtained from the bound germanium-68 which forms gallium-68 in situ by eluting the column with a hydrochloric acid solution to form an acidic solution of gallium-68. The acidic solution of gallium-68 can be neutralized.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1981},
month = {1}
}
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