Process for preparation of potassium-38

Lambrecht, Richard M; Wolf, Alfred P

Title: Process for preparation of potassium-38

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Abstract

A solution of potassium-38 suitable for use as a radiopharmaceutical and a method for its production. Argon is irradiated with protons having energies above the threshold for the .sup.40 Ar(p,3n).sup.38 K reaction. The resulting potassium-38 is dissolved in a sterile water and any contaminating chlorine-38 is removed.

Inventors:

Lambrecht, Richard M ^[1]; Wolf, Alfred P ^[2]

Quogue, NY
Setauket, NY

Issue Date:: 1981-01-01

Research Org.:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

OSTI Identifier:: 863808

Patent Number(s):: 4252668

Assignee:: United States of America as represented by United States (Washington, DC)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16D - COUPLINGS FOR TRANSMITTING ROTATION

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K2123/00 - Preparations for testing in vivo
A61K51/02 - characterised by the carrier {, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus}
A61K51/121 - {Solutions, i.e. homogeneous liquid formulation}
A61K51/1282 - {Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents}

F - MECHANICAL ENGINEERING F16 - ENGINEERING ELEMENTS AND UNITS F16D - COUPLINGS FOR TRANSMITTING ROTATION
F16D2001/062 - {characterised by adaptors where hub bores being larger than the shaft}

G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
G21G1/10 - by bombardment with electrically charged particles

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DOE Contract Number:: EY-76-C-02-0016

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: process; preparation; potassium-38; solution; suitable; radiopharmaceutical; method; production; argon; irradiated; protons; energies; threshold; sup40; arp3nsup38; reaction; resulting; dissolved; sterile; water; contaminating; chlorine-38; removed; /252/250/376/423/976/

Citation Formats


                    Lambrecht, Richard M, and Wolf, Alfred P. Process for preparation of potassium-38.  United States: N. p., 1981. 
        Web.

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                    Lambrecht, Richard M, & Wolf, Alfred P. Process for preparation of potassium-38.  United States.

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                    Lambrecht, Richard M, and Wolf, Alfred P. Thu .  
        "Process for preparation of potassium-38".  United States.  https://www.osti.gov/servlets/purl/863808.

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@article{osti_863808,

  title        = {Process for preparation of potassium-38},

  author       = {Lambrecht, Richard M and Wolf, Alfred P},

  abstractNote = {A solution of potassium-38 suitable for use as a radiopharmaceutical and a method for its production. Argon is irradiated with protons having energies above the threshold for the .sup.40 Ar(p,3n).sup.38 K reaction. The resulting potassium-38 is dissolved in a sterile water and any contaminating chlorine-38 is removed.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1981},

  month        = {1}

}

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