.sup.123m Te-Labeled biochemicals and method of preparation
Abstract
A novel class of .sup.123m Te-labeled steroids and amino acids is provided by the method of reacting a .sup.123m Te symmetric diorgano ditelluride with a hydride reducing agent and a source of alkali metal ions to form an alkali metal organo telluride. The alkali metal organo telluride is reacted with a primary halogenated steroidal side chain, amino acid, or amino acid precursor such as hydantoin. The novel compounds are useful as biological tracers and as organal imaging agents.
- Inventors:
-
- (Oak Ridge, TN)
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- OSTI Identifier:
- 863621
- Patent Number(s):
- 4215045
- Assignee:
- United States of America as represented by United States (Washington, DC)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 123m; te-labeled; biochemicals; method; preparation; novel; steroids; amino; acids; provided; reacting; symmetric; diorgano; ditelluride; hydride; reducing; agent; source; alkali; metal; form; organo; telluride; reacted; primary; halogenated; steroidal; chain; acid; precursor; hydantoin; compounds; useful; biological; tracers; organal; imaging; agents; biological tracer; imaging agents; amino acid; alkali metal; reducing agent; amino acids; novel compounds; imaging agent; novel compound; /999/376/
Citation Formats
Knapp, Jr., Furn F. .sup.123m Te-Labeled biochemicals and method of preparation. United States: N. p., 1980.
Web.
Knapp, Jr., Furn F. .sup.123m Te-Labeled biochemicals and method of preparation. United States.
Knapp, Jr., Furn F. Tue .
".sup.123m Te-Labeled biochemicals and method of preparation". United States. https://www.osti.gov/servlets/purl/863621.
@article{osti_863621,
title = {.sup.123m Te-Labeled biochemicals and method of preparation},
author = {Knapp, Jr., Furn F.},
abstractNote = {A novel class of .sup.123m Te-labeled steroids and amino acids is provided by the method of reacting a .sup.123m Te symmetric diorgano ditelluride with a hydride reducing agent and a source of alkali metal ions to form an alkali metal organo telluride. The alkali metal organo telluride is reacted with a primary halogenated steroidal side chain, amino acid, or amino acid precursor such as hydantoin. The novel compounds are useful as biological tracers and as organal imaging agents.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1980},
month = {1}
}
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.