Removal of plutonium from hepatic tissue

Title: Removal of plutonium from hepatic tissue

Full Record
Other Related Research

Abstract

A method is provided for removing plutonium from hepatic tissues by introducing into the body and blood stream a solution of the complexing agent DTPA and an adjunct thereto. The adjunct material induces aberrations in the hepatic tissue cells and removes intracellularly deposited plutonium which is normally unavailable for complexation with the DTPA. Once the intracellularly deposited plutonium has been removed from the cell by action of the adjunct material, it can be complexed with the DTPA present in the blood stream and subsequently removed from the body by normal excretory processes.

Inventors:

Lindenbaum, Arthur ^[1]; Rosenthal, Marcia W. ^[2]

(Lockport, IL)
(La Grange, IL)

Issue Date:: 1979-01-01

Research Org.:: Argonne National Laboratory (ANL), Argonne, IL

OSTI Identifier:: 863305

Patent Number(s):: 4143131

Assignee:: United States of America as represented by United States (Washington, DC) ANL

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: removal; plutonium; hepatic; tissue; method; provided; removing; tissues; introducing; blood; stream; solution; complexing; agent; dtpa; adjunct; thereto; material; induces; aberrations; cells; removes; intracellularly; deposited; normally; unavailable; complexation; removed; cell; action; complexed; subsequently; normal; excretory; processes; subsequently removed; complexing agent; subsequently remove; blood stream; hepatic tissue; /514/

Citation Formats


                    Lindenbaum, Arthur, and Rosenthal, Marcia W. Removal of plutonium from hepatic tissue.  United States: N. p., 1979. 
        Web.

Copy to clipboard


                    Lindenbaum, Arthur, & Rosenthal, Marcia W. Removal of plutonium from hepatic tissue.  United States.

Copy to clipboard


                    Lindenbaum, Arthur, and Rosenthal, Marcia W. Mon .  
        "Removal of plutonium from hepatic tissue".  United States.  https://www.osti.gov/servlets/purl/863305.

Copy to clipboard


                    
@article{osti_863305,

  title        = {Removal of plutonium from hepatic tissue},

  author       = {Lindenbaum, Arthur and Rosenthal, Marcia W.},

  abstractNote = {A method is provided for removing plutonium from hepatic tissues by introducing into the body and blood stream a solution of the complexing agent DTPA and an adjunct thereto. The adjunct material induces aberrations in the hepatic tissue cells and removes intracellularly deposited plutonium which is normally unavailable for complexation with the DTPA. Once the intracellularly deposited plutonium has been removed from the cell by action of the adjunct material, it can be complexed with the DTPA present in the blood stream and subsequently removed from the body by normal excretory processes.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1979},

  month        = {1}

}

Copy to clipboard

Patent:

View Patent

Save / Share:

Export Metadata

Save to My Library

Similar records in DOE Patents and OSTI.GOV collections:

Removal of plutonium from hepatic tissue

Patent Lindenbaum, A.; Rosenthal, M.W.

A method is provided for removing plutonium from hepatic tissues by introducing into the body and blood stream a solution of the complexing agent DTPA and an adjunct thereto. The adjunct material induces aberrations in the hepatic tissue cells and removes intracellularly deposited plutonium which is normally unavailable for complexation with the DTPA. Once the intracellularly deposited plutonium has been removed from the cell by action of the adjunct material, it can be complexed with the DTPA present in the blood stream and subsequently removed from the body by normal excretory processes.
Removal of plutonium and americium from alkaline waste solutions

Patent Schulz, Wallace W. (Richland, WA)

High salt content, alkaline waste solutions containing plutonium and americium are contacted with a sodium titanate compound to effect removal of the plutonium and americium from the alkaline waste solution onto the sodium titanate and provide an effluent having a radiation level of less than 10 nCi per gram alpha emitters.
Full Text Available
Method for removal of plutonium impurity from americium oxides and fluorides

Patent FitzPatrick, John R. (Los Alamos, NM); Dunn, Jerry G. (Los Alamos, NM); Avens, Larry R. (Los Alamos, NM)

Method for removal of plutonium impurity from americium oxides and fluorides. AmF.sub.4 is not further oxidized to AmF.sub.6 by the application of O.sub.2 F at room temperature, while plutonium compounds present in the americium sample are fluorinated to volatile PuF.sub.6, which can readily be separated therefrom, leaving the purified americium oxides and/or fluorides as the solid tetrafluoride.
Full Text Available
Platelet aggregating material from equine arterial tissue

Patent Schneider, Morris D. (Knoxville, TN)

Novel hemostatic agent comprises equine arterial fibrillar collagen in a carrier. The agent is useful for the aggregation of platelets for clinical diagnostic tests and for the clotting of blood, such as for controlling bleeding in warm blooded species. The fibrillar collagen is obtained by extracting homogenized equine arterial tissue with aqueous solutions followed by extensive dialysis.
Full Text Available
Combinational pixel-by-pixel and object-level classifying, segmenting, and agglomerating in performing quantitative image analysis that distinguishes between healthy non-cancerous and cancerous cell nuclei and delineates nuclear, cytoplasm, and stromal material objects from stained biological tissue materials

Patent Boucheron, Laura E

Quantitative object and spatial arrangement-level analysis of tissue are detailed using expert (pathologist) input to guide the classification process. A two-step method is disclosed for imaging tissue, by classifying one or more biological materials, e.g. nuclei, cytoplasm, and stroma, in the tissue into one or more identified classes on a pixel-by-pixel basis, and segmenting the identified classes to agglomerate one or more sets of identified pixels into segmented regions. Typically, the one or more biological materials comprises nuclear material, cytoplasm material, and stromal material. The method further allows a user to markup the image subsequent to the classification to re-classifymore »« less
Full Text Available

Similar Records