Production of .sup.203 Pb-tris-hydroxymethyl amino methane

Lambrecht, Richard M; Packer, Samuel; Merrill, Jerald C; Atkins, Harold L; Wolf, Alfred P; Bradley-Moore, Patrick R

Title: Production of .sup.203 Pb-tris-hydroxymethyl amino methane

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Abstract

.sup.203 Pb-tris complex injected for use in the detection and localization of tumors. The lead-203 is produced from the deuteron bombardment of a thallium target and chemically separated from the thallium. The tris is added which complexes with the lead-203.

Inventors:

Lambrecht, Richard M ^[1]; Packer, Samuel ^[2]; Merrill, Jerald C ^[3]; Atkins, Harold L ^[4]; Wolf, Alfred P ^[4]; Bradley-Moore, Patrick R ^[5]

East Quogue, NY
Manhasset, NY
Salt Lake City, UT
Setauket, NY
New York, NY

Issue Date:: 1977-01-01

Research Org.:: Brookhaven National Lab. (BNL), Upton, NY (United States)

OSTI Identifier:: 862779

Patent Number(s):: 4011307

Assignee:: United States of America as represented by United States Energy (Washington, DC)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

G - PHYSICS G21 - NUCLEAR PHYSICS G21H - OBTAINING ENERGY FROM RADIOACTIVE SOURCES

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K2123/00 - Preparations for testing in vivo
A61K51/0478 - {complexes from non-cyclic ligands, e.g. EDTA, MAG3}

G - PHYSICS G21 - NUCLEAR PHYSICS G21H - OBTAINING ENERGY FROM RADIOACTIVE SOURCES
G21H5/02 - as tracers

G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
G21G1/10 - by bombardment with electrically charged particles

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DOE Contract Number:: AT(30-1)-16

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: production; 203; pb-tris-hydroxymethyl; amino; methane; pb-tris; complex; injected; detection; localization; tumors; lead-203; produced; deuteron; bombardment; thallium; target; chemically; separated; tris; added; complexes; thallium target; /424/250/376/423/999/976/

Citation Formats


                    Lambrecht, Richard M, Packer, Samuel, Merrill, Jerald C, Atkins, Harold L, Wolf, Alfred P, and Bradley-Moore, Patrick R. Production of .sup.203 Pb-tris-hydroxymethyl amino methane.  United States: N. p., 1977. 
        Web.

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                    Lambrecht, Richard M, Packer, Samuel, Merrill, Jerald C, Atkins, Harold L, Wolf, Alfred P, & Bradley-Moore, Patrick R. Production of .sup.203 Pb-tris-hydroxymethyl amino methane.  United States.

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                    Lambrecht, Richard M, Packer, Samuel, Merrill, Jerald C, Atkins, Harold L, Wolf, Alfred P, and Bradley-Moore, Patrick R. Sat .  
        "Production of .sup.203 Pb-tris-hydroxymethyl amino methane".  United States.  https://www.osti.gov/servlets/purl/862779.

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@article{osti_862779,

  title        = {Production of .sup.203 Pb-tris-hydroxymethyl amino methane},

  author       = {Lambrecht, Richard M and Packer, Samuel and Merrill, Jerald C and Atkins, Harold L and Wolf, Alfred P and Bradley-Moore, Patrick R},

  abstractNote = {.sup.203 Pb-tris complex injected for use in the detection and localization of tumors. The lead-203 is produced from the deuteron bombardment of a thallium target and chemically separated from the thallium. The tris is added which complexes with the lead-203.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1977},

  month        = {1}

}

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