Production of high purity radiothallium

Title: Production of high purity radiothallium

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Abstract

The method of producing high purity thallium-201 for use as a myocardial scanning agent comprising the steps of irradiating a thallium target with protons to give the reaction .sup.203 Tl(p,3n) .sup.201.sub.Pb, separating in ion exchange columns the lead from the thallium isotopes, permitting the lead to decay, and then purifying the thallium solution and converting the thallium present to thallous form in which it can be used.

Inventors:

Lebowitz, Elliot ^[1]; Greene, Margaret W ^[2]

Brookline, MA
Bellport, NY

Issue Date:: 1976-11-23

Research Org.:: Brookhaven National Lab. (BNL), Upton, NY (United States)

OSTI Identifier:: 862706

Patent Number(s):: 3993538

Application Number:: 05/646,781

Assignee:: United States of America as represented by United States Energy (Washington, DC)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K2123/00 - Preparations for testing in vivo
A61K51/1282 - {Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents}

G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
G21G1/10 - by bombardment with electrically charged particles

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DOE Contract Number:: AT(30-1)-16

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: production; purity; radiothallium; method; producing; thallium-201; myocardial; scanning; agent; comprising; steps; irradiating; thallium; target; protons; reaction; 203; 3n; 201; pb; separating; exchange; columns; lead; isotopes; permitting; decay; purifying; solution; converting; thallous; form; exchange column; thallium target; agent comprising; /376/976/

Citation Formats


                    Lebowitz, Elliot, and Greene, Margaret W. Production of high purity radiothallium.  United States: N. p., 1976. 
        Web.

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                    Lebowitz, Elliot, & Greene, Margaret W. Production of high purity radiothallium.  United States.

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                    Lebowitz, Elliot, and Greene, Margaret W. Tue .  
        "Production of high purity radiothallium".  United States.  https://www.osti.gov/servlets/purl/862706.

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@article{osti_862706,

  title        = {Production of high purity radiothallium},

  author       = {Lebowitz, Elliot and Greene, Margaret W},

  abstractNote = {The method of producing high purity thallium-201 for use as a myocardial scanning agent comprising the steps of irradiating a thallium target with protons to give the reaction .sup.203 Tl(p,3n) .sup.201.sub.Pb, separating in ion exchange columns the lead from the thallium isotopes, permitting the lead to decay, and then purifying the thallium solution and converting the thallium present to thallous form in which it can be used.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1976},

  month        = {11}

}

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