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Title: Kit for the rapid preparation of .sup.99m Tc red blood cells

Abstract

A method and sample kit for the preparation of .sup.99m Tc-labeled red blood cells in a closed, sterile system. A partially evacuated tube, containing a freeze-dried stannous citrate formulation with heparin as an anticoagulant, allows whole blood to be automatically drawn from the patient. The radioisotope is added at the end of the labeling sequence to minimize operator exposure. Consistent 97% yields in 20 minutes are obtained with small blood samples. Freeze-dried kits have remained stable after five months.

Inventors:
 [1];  [2]
  1. Bayport, NY
  2. St. Ann, MO
Issue Date:
Research Org.:
Brookhaven National Lab. (BNL), Upton, NY (United States)
OSTI Identifier:
862680
Patent Number(s):
3988429
Assignee:
United States of America as represented by United States Energy (Washington, DC)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
DOE Contract Number:  
AT(30-1)-16
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
kit; rapid; preparation; 99m; tc; blood; cells; method; sample; tc-labeled; closed; sterile; partially; evacuated; tube; containing; freeze-dried; stannous; citrate; formulation; heparin; anticoagulant; allows; automatically; drawn; patient; radioisotope; added; labeling; sequence; minimize; operator; exposure; consistent; 97; yields; 20; minutes; obtained; samples; kits; remained; stable; five; months; blood sample; blood samples; blood cells; blood cell; partially evacuated; evacuated tube; /424/422/999/

Citation Formats

Richards, Powell, and Smith, Terry D. Kit for the rapid preparation of .sup.99m Tc red blood cells. United States: N. p., 1976. Web.
Richards, Powell, & Smith, Terry D. Kit for the rapid preparation of .sup.99m Tc red blood cells. United States.
Richards, Powell, and Smith, Terry D. Thu . "Kit for the rapid preparation of .sup.99m Tc red blood cells". United States. https://www.osti.gov/servlets/purl/862680.
@article{osti_862680,
title = {Kit for the rapid preparation of .sup.99m Tc red blood cells},
author = {Richards, Powell and Smith, Terry D},
abstractNote = {A method and sample kit for the preparation of .sup.99m Tc-labeled red blood cells in a closed, sterile system. A partially evacuated tube, containing a freeze-dried stannous citrate formulation with heparin as an anticoagulant, allows whole blood to be automatically drawn from the patient. The radioisotope is added at the end of the labeling sequence to minimize operator exposure. Consistent 97% yields in 20 minutes are obtained with small blood samples. Freeze-dried kits have remained stable after five months.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1976},
month = {1}
}

Patent:

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