Kit for the rapid preparation of .sup.99m Tc red blood cells
Abstract
A method and sample kit for the preparation of .sup.99m Tc-labeled red blood cells in a closed, sterile system. A partially evacuated tube, containing a freeze-dried stannous citrate formulation with heparin as an anticoagulant, allows whole blood to be automatically drawn from the patient. The radioisotope is added at the end of the labeling sequence to minimize operator exposure. Consistent 97% yields in 20 minutes are obtained with small blood samples. Freeze-dried kits have remained stable after five months.
- Inventors:
-
- Bayport, NY
- St. Ann, MO
- Issue Date:
- Research Org.:
- Brookhaven National Laboratory (BNL), Upton, NY (United States)
- OSTI Identifier:
- 862680
- Patent Number(s):
- 3988429
- Assignee:
- United States of America as represented by United States Energy (Washington, DC)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- AT(30-1)-16
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- kit; rapid; preparation; 99m; tc; blood; cells; method; sample; tc-labeled; closed; sterile; partially; evacuated; tube; containing; freeze-dried; stannous; citrate; formulation; heparin; anticoagulant; allows; automatically; drawn; patient; radioisotope; added; labeling; sequence; minimize; operator; exposure; consistent; 97; yields; 20; minutes; obtained; samples; kits; remained; stable; five; months; blood sample; blood samples; blood cells; blood cell; partially evacuated; evacuated tube; /424/422/999/
Citation Formats
Richards, Powell, and Smith, Terry D. Kit for the rapid preparation of .sup.99m Tc red blood cells. United States: N. p., 1976.
Web.
Richards, Powell, & Smith, Terry D. Kit for the rapid preparation of .sup.99m Tc red blood cells. United States.
Richards, Powell, and Smith, Terry D. Thu .
"Kit for the rapid preparation of .sup.99m Tc red blood cells". United States. https://www.osti.gov/servlets/purl/862680.
@article{osti_862680,
title = {Kit for the rapid preparation of .sup.99m Tc red blood cells},
author = {Richards, Powell and Smith, Terry D},
abstractNote = {A method and sample kit for the preparation of .sup.99m Tc-labeled red blood cells in a closed, sterile system. A partially evacuated tube, containing a freeze-dried stannous citrate formulation with heparin as an anticoagulant, allows whole blood to be automatically drawn from the patient. The radioisotope is added at the end of the labeling sequence to minimize operator exposure. Consistent 97% yields in 20 minutes are obtained with small blood samples. Freeze-dried kits have remained stable after five months.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 1976},
month = {Thu Jan 01 00:00:00 EST 1976}
}
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