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Title: Stable radiometal antibody immunoconjugates

Abstract

The present invention relates to new rigid chelating structures, to methods for preparing these materials, and to their use in preparing radiometal labeled immunoconjugates. These new chelates include cyclohexyl EDTA monohydride, the trans forms of cyclohexyl DTPA and TTHA, and derivatives of these cyclohexyl polyaminocarboxylate materials. No Drawings

Inventors:
; ;
Issue Date:
OSTI Identifier:
7199488
Patent Number(s):
5334729
Application Number:
PPN: US 7-787244
Assignee:
Associated Universities, Inc., Washington, DC (United States)
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Resource Relation:
Patent File Date: 4 Nov 1991
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CHELATING AGENTS; CHEMICAL PREPARATION; RADIOPHARMACEUTICALS; RADIOIMMUNOASSAY; USES; BIOASSAY; DIAGNOSTIC TECHNIQUES; DRUGS; IMMUNOASSAY; ISOTOPE APPLICATIONS; LABELLED COMPOUNDS; RADIOASSAY; RADIOIMMUNODETECTION; SYNTHESIS; TRACER TECHNIQUES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics

Citation Formats

Mease, R C, Srivastava, S C, and Gestin, J F. Stable radiometal antibody immunoconjugates. United States: N. p., 1994. Web.
Mease, R C, Srivastava, S C, & Gestin, J F. Stable radiometal antibody immunoconjugates. United States.
Mease, R C, Srivastava, S C, and Gestin, J F. Tue . "Stable radiometal antibody immunoconjugates". United States.
@article{osti_7199488,
title = {Stable radiometal antibody immunoconjugates},
author = {Mease, R C and Srivastava, S C and Gestin, J F},
abstractNote = {The present invention relates to new rigid chelating structures, to methods for preparing these materials, and to their use in preparing radiometal labeled immunoconjugates. These new chelates include cyclohexyl EDTA monohydride, the trans forms of cyclohexyl DTPA and TTHA, and derivatives of these cyclohexyl polyaminocarboxylate materials. No Drawings},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1994},
month = {8}
}