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Title: Multiplexed fluorescence detector system for capillary electrophoresis

Abstract

A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis. 14 figures.

Inventors:
;
Issue Date:
OSTI Identifier:
7174187
Patent Number(s):
5324401 A
Application Number:
PPN: US 8-013960
Assignee:
Iowa State University Research Foundation, Inc., Ames, IA (United States) PTO; EDB-94-110787
DOE Contract Number:  
W-7405-ENG-82
Resource Type:
Patent
Resource Relation:
Patent File Date: 5 Feb 1993
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; ELECTROPHORESIS; MONITORS; DESIGN; CAPILLARY FLOW; DATA ANALYSIS; FIBER OPTICS; FLUORESCENCE; LASER RADIATION; SEPARATION PROCESSES; ELECTROMAGNETIC RADIATION; FLUID FLOW; LUMINESCENCE; MEASURING INSTRUMENTS; RADIATIONS; 400105* - Separation Procedures

Citation Formats

Yeung, E.S., and Taylor, J.A. Multiplexed fluorescence detector system for capillary electrophoresis. United States: N. p., 1994. Web.
Yeung, E.S., & Taylor, J.A. Multiplexed fluorescence detector system for capillary electrophoresis. United States.
Yeung, E.S., and Taylor, J.A. Tue . "Multiplexed fluorescence detector system for capillary electrophoresis". United States.
@article{osti_7174187,
title = {Multiplexed fluorescence detector system for capillary electrophoresis},
author = {Yeung, E.S. and Taylor, J.A.},
abstractNote = {A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis. 14 figures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1994},
month = {6}
}