Multiplexed fluorescence detector system for capillary electrophoresis
Abstract
A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis. 14 figures.
- Inventors:
- Issue Date:
- OSTI Identifier:
- 7174187
- Patent Number(s):
- 5324401
- Application Number:
- PPN: US 8-013960
- Assignee:
- Iowa State University Research Foundation, Inc., Ames, IA (United States)
- DOE Contract Number:
- W-7405-ENG-82
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 5 Feb 1993
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; ELECTROPHORESIS; MONITORS; DESIGN; CAPILLARY FLOW; DATA ANALYSIS; FIBER OPTICS; FLUORESCENCE; LASER RADIATION; SEPARATION PROCESSES; ELECTROMAGNETIC RADIATION; FLUID FLOW; LUMINESCENCE; MEASURING INSTRUMENTS; RADIATIONS; 400105* - Separation Procedures
Citation Formats
Yeung, E S, and Taylor, J A. Multiplexed fluorescence detector system for capillary electrophoresis. United States: N. p., 1994.
Web.
Yeung, E S, & Taylor, J A. Multiplexed fluorescence detector system for capillary electrophoresis. United States.
Yeung, E S, and Taylor, J A. Tue .
"Multiplexed fluorescence detector system for capillary electrophoresis". United States.
@article{osti_7174187,
title = {Multiplexed fluorescence detector system for capillary electrophoresis},
author = {Yeung, E S and Taylor, J A},
abstractNote = {A fluorescence detection system for capillary electrophoresis is provided wherein the detection system can simultaneously excite fluorescence and substantially simultaneously monitor separations in multiple capillaries. This multiplexing approach involves laser irradiation of a sample in a plurality of capillaries through optical fibers that are coupled individually with the capillaries. The array is imaged orthogonally through a microscope onto a charge-coupled device camera for signal analysis. 14 figures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1994},
month = {6}
}
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