Vaccine to Control the Viral Infection of Fish.

Title: Vaccine to Control the Viral Infection of Fish.

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Subunit vaccines and their use for immunizing fish against infection by viruses are disclosed. In particular, plasmid pG8 is constructed by joining, with the plasmid pUC8, DNA which encodes the glycoprotein of infectious hematopoietic necrosis virus (IHNV). E. coli cells are transformed by pG8, whereby pure viral antigen is produced to provide a vaccine for the control of IHNV in fish. 10 figs.

Inventors:: Leong, JoAnn Ching

Issue Date:: 1994-10-11

OSTI Identifier:: 7100725

Assignee:: Oregon State Univ., Eugene, OR (United States) BPA; EDB-94-170395

Patent Number(s):: US 5354555; A

Application Number:: CNN: 901-15-139; PPN: US 8-027742

Contract Number:: AI79-84BP16479

Resource Relation:: Patent File Date: 8 Mar 1993

Research Org:: United States. Bonneville Power Administration.

Sponsoring Org:: USDOE

Country of Publication:: United States

Language:: English

Subject:: 60 APPLIED LIFE SCIENCES; FISHES; VIRAL DISEASES; VACCINES; SYNTHESIS; VIRUSES; ANIMALS; AQUATIC ORGANISMS; DISEASES; INFECTIOUS DISEASES; MICROORGANISMS; PARASITES; VERTEBRATES; Salmon - Diseases; Steelhead (Fish) - Diseases; Viral vaccines; Fishes - Diseases; 553003* - Agriculture & Food Technology- Pest & Disease Control- (1987-)

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Subunit vaccines and their use for immunizing fish against infection by viruses are disclosed. In particular, plasmid pG8 is constructed by joining, with the plasmid pUC8, DNA which encodes the glycoprotein of infectious hematopoietic necrosis virus (IHNV). E. coli cells are transformed by pG8, whereby pure viral antigen is produced to provide a vaccine for the control of IHNV in fish.
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