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Title: Interface for liquid chromatograph-mass spectrometer

Abstract

A moving belt interface is described for real-time, high-performance liquid chromatograph (HPLC)/mass spectrometer (MS) analysis which strips away the HPLC solvent as it emerges from the end of the HPLC column and leaves a residue suitable for mass-spectral analysis. The interface includes a portable, stand-alone apparatus having a plural stage vacuum station, a continuous ribbon or belt, a drive train magnetically coupled to an external drive motor, a calibrated HPLC delivery system, a heated probe tip and means located adjacent the probe tip for direct ionization of the residue on the belt. The interface is also capable of being readily adapted to fit any mass spectrometer. 8 figs.

Inventors:
;
Issue Date:
OSTI Identifier:
7070224
Patent Number(s):
4867947 A
Application Number:
PPN: US 6-904953
Assignee:
Sepragen Corp., San Leandro, CA (United States) PTO; EDB-94-117256
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Resource Relation:
Patent File Date: 8 Sep 1986
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; EXTRACTION COLUMNS; EQUIPMENT INTERFACES; MASS SPECTROMETERS; DESIGN; LIQUID COLUMN CHROMATOGRAPHY; OPERATION; REMOVAL; SOLVENTS; CHROMATOGRAPHY; EXTRACTION APPARATUSES; MEASURING INSTRUMENTS; SEPARATION EQUIPMENT; SEPARATION PROCESSES; SPECTROMETERS; 400105* - Separation Procedures; 400102 - Chemical & Spectral Procedures

Citation Formats

Andresen, B.D., and Fought, E.R. Interface for liquid chromatograph-mass spectrometer. United States: N. p., 1989. Web.
Andresen, B.D., & Fought, E.R. Interface for liquid chromatograph-mass spectrometer. United States.
Andresen, B.D., and Fought, E.R. Tue . "Interface for liquid chromatograph-mass spectrometer". United States.
@article{osti_7070224,
title = {Interface for liquid chromatograph-mass spectrometer},
author = {Andresen, B.D. and Fought, E.R.},
abstractNote = {A moving belt interface is described for real-time, high-performance liquid chromatograph (HPLC)/mass spectrometer (MS) analysis which strips away the HPLC solvent as it emerges from the end of the HPLC column and leaves a residue suitable for mass-spectral analysis. The interface includes a portable, stand-alone apparatus having a plural stage vacuum station, a continuous ribbon or belt, a drive train magnetically coupled to an external drive motor, a calibrated HPLC delivery system, a heated probe tip and means located adjacent the probe tip for direct ionization of the residue on the belt. The interface is also capable of being readily adapted to fit any mass spectrometer. 8 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1989},
month = {9}
}