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Title: Liquid-phase chromatography detector

Abstract

A liquid-phase chromatography detector comprises a flow cell having an inlet tubular conduit for receiving a liquid chromatographic effluent and discharging it as a flowing columnar stream onto a vertically adjustable receiving surface spaced apart from and located vertically below and in close proximity to the discharge end of the tubular conduit; a receiver adapted to receive liquid overflowing from the receiving surface; an exit conduit for continuously removing liquid from the receiver; a light source for focusing fluorescence-producing light pulses on the flowing columnar stream as it passes from the outlet of the conduit to the receiving surface and a fluorescence detector to detect the produced fluorescence; a source of light pulse for producing acoustic waves in the columnar stream as it passes from the conduit outlet to the receiving surface; and a piezoelectric transducer adapted to detect those waves; and a source of bias voltage applied to the inlet tubular conduit and adapted to produce ionization of the liquid flowing through the flow cell so as to produce photocurrents therein and an electrical system to detect and record the photocurrents. This system is useful in separating and detecting individual chemical compounds from mixtures thereof. 5 figs.

Inventors:
; ;
Issue Date:
Research Org.:
University of Florida
Sponsoring Org.:
USDOE
OSTI Identifier:
7004222
Patent Number(s):
4413504 A
Application Number:
PPN: US 6-382633
Assignee:
Univ. of Florida, Gainesville, FL (United States) ORO; EDB-94-124771
DOE Contract Number:  
AS05-78OR06022
Resource Type:
Patent
Resource Relation:
Patent File Date: 27 May 1982
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; LIQUID COLUMN CHROMATOGRAPHY; MONITORS; MIXTURES; DESIGN; CHEMICAL ANALYSIS; FLUORESCENCE; IONIZATION; LIQUID FLOW; SEPARATION PROCESSES; SOUND WAVES; CHROMATOGRAPHY; DISPERSIONS; FLUID FLOW; LUMINESCENCE; MEASURING INSTRUMENTS; 400105* - Separation Procedures; 400102 - Chemical & Spectral Procedures

Citation Formats

Voigtman, E.G., Winefordner, J.D., and Jurgensen, A.R. Liquid-phase chromatography detector. United States: N. p., 1983. Web.
Voigtman, E.G., Winefordner, J.D., & Jurgensen, A.R. Liquid-phase chromatography detector. United States.
Voigtman, E.G., Winefordner, J.D., and Jurgensen, A.R. Tue . "Liquid-phase chromatography detector". United States.
@article{osti_7004222,
title = {Liquid-phase chromatography detector},
author = {Voigtman, E.G. and Winefordner, J.D. and Jurgensen, A.R.},
abstractNote = {A liquid-phase chromatography detector comprises a flow cell having an inlet tubular conduit for receiving a liquid chromatographic effluent and discharging it as a flowing columnar stream onto a vertically adjustable receiving surface spaced apart from and located vertically below and in close proximity to the discharge end of the tubular conduit; a receiver adapted to receive liquid overflowing from the receiving surface; an exit conduit for continuously removing liquid from the receiver; a light source for focusing fluorescence-producing light pulses on the flowing columnar stream as it passes from the outlet of the conduit to the receiving surface and a fluorescence detector to detect the produced fluorescence; a source of light pulse for producing acoustic waves in the columnar stream as it passes from the conduit outlet to the receiving surface; and a piezoelectric transducer adapted to detect those waves; and a source of bias voltage applied to the inlet tubular conduit and adapted to produce ionization of the liquid flowing through the flow cell so as to produce photocurrents therein and an electrical system to detect and record the photocurrents. This system is useful in separating and detecting individual chemical compounds from mixtures thereof. 5 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1983},
month = {11}
}