1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof

Title: 1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof

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Abstract

The novel labelled compound 1-/sup 11/C-2-deoxy-D-glucose, and a process for its preparation from 2,3:4,5-di-O-isopropylidene-D-arabinitol derivatives of relatively high reactivity are disclosed. 1-/sup 11/C-2-deoxy-D-glucose is useful for measuring regional brain glucose metabolism in vivo.

Inventors:: MacGregor, R R; Wolf, A P; Shiue, C Y; Wan, C N

Issue Date:: 1980-02-08

OSTI Identifier:: 6921489

Assignee:: Dept. of Energy

DOE Contract Number:: EY-76-C-02-0016

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; CARBON 11; RADIOPHARMACEUTICALS; GLUCOSE; CHEMICAL PREPARATION; BRAIN; IN VIVO; METABOLISM; METABOLITES; ALDEHYDES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBOHYDRATES; CARBON ISOTOPES; CENTRAL NERVOUS SYSTEM; DRUGS; EVEN-ODD NUCLEI; HEXOSES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; MINUTES LIVING RADIOISOTOPES; MONOSACCHARIDES; NERVOUS SYSTEM; NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SACCHARIDES; SYNTHESIS; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550501 - Metabolism- Tracer Techniques; 551001 - Physiological Systems- Tracer Techniques; 400702 - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials

Citation Formats


                    MacGregor, R R, Wolf, A P, Shiue, C Y, and Wan, C N. 1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof.  United States: N. p., 1980. 
        Web.

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                    MacGregor, R R, Wolf, A P, Shiue, C Y, & Wan, C N. 1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof.  United States.

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                    MacGregor, R R, Wolf, A P, Shiue, C Y, and Wan, C N. Fri .  
        "1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof".  United States.

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@article{osti_6921489,

  title        = {1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof},

  author       = {MacGregor, R R and Wolf, A P and Shiue, C Y and Wan, C N},

  abstractNote = {The novel labelled compound 1-/sup 11/C-2-deoxy-D-glucose, and a process for its preparation from 2,3:4,5-di-O-isopropylidene-D-arabinitol derivatives of relatively high reactivity are disclosed. 1-/sup 11/C-2-deoxy-D-glucose is useful for measuring regional brain glucose metabolism in vivo.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1980},

  month        = {2}

}

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