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Title: 1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof

Abstract

The novel labelled compound 1-/sup 11/C-2-deoxy-D-glucose, and a process for its preparation from 2,3:4,5-di-O-isopropylidene-D-arabinitol derivatives of relatively high reactivity are disclosed. 1-/sup 11/C-2-deoxy-D-glucose is useful for measuring regional brain glucose metabolism in vivo.

Inventors:
; ; ;
Issue Date:
OSTI Identifier:
6921489
Assignee:
Dept. of Energy TIC; EDB-81-035176
DOE Contract Number:  
EY-76-C-02-0016
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; CARBON 11; RADIOPHARMACEUTICALS; GLUCOSE; CHEMICAL PREPARATION; BRAIN; IN VIVO; METABOLISM; METABOLITES; ALDEHYDES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBOHYDRATES; CARBON ISOTOPES; CENTRAL NERVOUS SYSTEM; DRUGS; EVEN-ODD NUCLEI; HEXOSES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; MINUTES LIVING RADIOISOTOPES; MONOSACCHARIDES; NERVOUS SYSTEM; NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SACCHARIDES; SYNTHESIS 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics; 550501 -- Metabolism-- Tracer Techniques; 551001 -- Physiological Systems-- Tracer Techniques; 400702 -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials

Citation Formats

MacGregor, R.R., Wolf, A.P., Shiue, C.Y., and Wan, C.N. 1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof. United States: N. p., 1980. Web.
MacGregor, R.R., Wolf, A.P., Shiue, C.Y., & Wan, C.N. 1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof. United States.
MacGregor, R.R., Wolf, A.P., Shiue, C.Y., and Wan, C.N. Fri . "1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof". United States.
@article{osti_6921489,
title = {1-/sup 11/C-2-deoxy-D-glucose and process for the preparation thereof},
author = {MacGregor, R.R. and Wolf, A.P. and Shiue, C.Y. and Wan, C.N.},
abstractNote = {The novel labelled compound 1-/sup 11/C-2-deoxy-D-glucose, and a process for its preparation from 2,3:4,5-di-O-isopropylidene-D-arabinitol derivatives of relatively high reactivity are disclosed. 1-/sup 11/C-2-deoxy-D-glucose is useful for measuring regional brain glucose metabolism in vivo.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1980},
month = {2}
}