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Title: Process for the production of 5'-deoxy-5-(/sup 18/F)fluorouridine

Abstract

Process for the production of 5'-deoxy-5-fluorouridine and the corresponding /sup 18/F compound by the reaction of fluorine or acetyl hypofluorite with 2', 3'-di-O-acetyl-5'-deoxyuridine followed by hydrolysis.

Inventors:
; ;
Issue Date:
OSTI Identifier:
6855564
Application Number:
ON: DE84011040
Assignee:
Dept. of Energy ERA-09-026563; EDB-84-084643
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Resource Relation:
Other Information: Portions are illegible in microfiche products
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; 62 RADIOLOGY AND NUCLEAR MEDICINE; FUDR; CHEMICAL PREPARATION; LABELLING; LABELLED COMPOUNDS; RADIOCHEMISTRY; RADIOTHERAPY; ANTI-INFECTIVE AGENTS; ANTIMETABOLITES; ANTIMICROBIAL AGENTS; AZINES; CHEMISTRY; DRUGS; FLUOROURACILS; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; MEDICINE; NUCLEAR MEDICINE; NUCLEOSIDES; NUCLEOTIDES; ORGANIC COMPOUNDS; ORGANIC FLUORINE COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PYRIMIDINES; RADIOLOGY; RADIOSENSITIZERS; RIBOSIDES; SYNTHESIS; THERAPY; URACILS 400702* -- Radiochemistry & Nuclear Chemistry-- Properties of Radioactive Materials; 550604 -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)

Citation Formats

Shiue, C.Y., Wolf, A.P., and Friedkin, M. Process for the production of 5'-deoxy-5-(/sup 18/F)fluorouridine. United States: N. p., 1983. Web.
Shiue, C.Y., Wolf, A.P., & Friedkin, M. Process for the production of 5'-deoxy-5-(/sup 18/F)fluorouridine. United States.
Shiue, C.Y., Wolf, A.P., and Friedkin, M. Wed . "Process for the production of 5'-deoxy-5-(/sup 18/F)fluorouridine". United States.
@article{osti_6855564,
title = {Process for the production of 5'-deoxy-5-(/sup 18/F)fluorouridine},
author = {Shiue, C.Y. and Wolf, A.P. and Friedkin, M.},
abstractNote = {Process for the production of 5'-deoxy-5-fluorouridine and the corresponding /sup 18/F compound by the reaction of fluorine or acetyl hypofluorite with 2', 3'-di-O-acetyl-5'-deoxyuridine followed by hydrolysis.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1983},
month = {8}
}