Electro-osmotically driven liquid delivery method and apparatus
Abstract
Method and apparatus are disclosed for controlling precisely the composition and delivery of liquid at sub-{micro}L/min flow rate. One embodiment of such a delivery system is an electro-osmotically driven gradient flow delivery system that generates dynamic gradient flows with sub-{micro}L/min flow rates by merging a plurality of electro-osmotic flows. These flows are delivered by a plurality of delivery arms attached to a mixing connector, where they mix and then flow into a receiving means, preferably a column. Each inlet of the plurality of delivery arms is placed in a corresponding solution reservoir. A plurality of independent programmable high-voltage power supplies is used to apply a voltage program to each of the plurality of solution reservoirs to regulate the electro-osmotic flow in each delivery arm. The electro-osmotic flow rates in the delivery arms are changed with time according to each voltage program to deliver the required gradient profile to the column. 4 figs.
- Inventors:
- Issue Date:
- Research Org.:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 678557
- Patent Number(s):
- 5942093
- Application Number:
- PAN: 8-878,470
- Assignee:
- Sandia Corp., Livermore, CA (United States)
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 24 Aug 1999
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING NOT INCLUDED IN OTHER CATEGORIES; FLOW REGULATORS; LIQUIDS; DESIGN; FLOW RATE; CHEMICAL COMPOSITION; PROCESS CONTROL; MIXTURES; ELECTRIC POTENTIAL
Citation Formats
Rakestraw, D J, Anex, D S, Yan, C, Dadoo, R, and Zare, R N. Electro-osmotically driven liquid delivery method and apparatus. United States: N. p., 1999.
Web.
Rakestraw, D J, Anex, D S, Yan, C, Dadoo, R, & Zare, R N. Electro-osmotically driven liquid delivery method and apparatus. United States.
Rakestraw, D J, Anex, D S, Yan, C, Dadoo, R, and Zare, R N. Tue .
"Electro-osmotically driven liquid delivery method and apparatus". United States.
@article{osti_678557,
title = {Electro-osmotically driven liquid delivery method and apparatus},
author = {Rakestraw, D J and Anex, D S and Yan, C and Dadoo, R and Zare, R N},
abstractNote = {Method and apparatus are disclosed for controlling precisely the composition and delivery of liquid at sub-{micro}L/min flow rate. One embodiment of such a delivery system is an electro-osmotically driven gradient flow delivery system that generates dynamic gradient flows with sub-{micro}L/min flow rates by merging a plurality of electro-osmotic flows. These flows are delivered by a plurality of delivery arms attached to a mixing connector, where they mix and then flow into a receiving means, preferably a column. Each inlet of the plurality of delivery arms is placed in a corresponding solution reservoir. A plurality of independent programmable high-voltage power supplies is used to apply a voltage program to each of the plurality of solution reservoirs to regulate the electro-osmotic flow in each delivery arm. The electro-osmotic flow rates in the delivery arms are changed with time according to each voltage program to deliver the required gradient profile to the column. 4 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1999},
month = {8}
}