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Title: Processing of hydroxylapatite coatings on titanium alloy bone prostheses

Abstract

Processing of hydroxylapatite sol-gel films on titanium alloy bone prostheses. A method utilizing non-line-of-sight ion beam implantation and/or rapid thermal processing to provide improved bonding of layers of hydroxylapatite to titanium alloy substrates while encouraging bone ingrowth into the hydroxylapatite layers located away from the substrate, is described for the fabrication of prostheses. The first layer of hydroxylapatite is mixed into the substrate by the ions or rapidly thermally annealed, while subsequent layers are heat treated or densified using ion implantation to form layers of decreasing density and larger crystallization, with the outermost layers being suitable for bone ingrowth.

Inventors:
; ; ;
Issue Date:
Research Org.:
University of California
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
675871
Patent Number(s):
5,817,326
Application Number:
PAN: 8-566,339
Assignee:
Univ. of California, Los Alamos, NM (United States) PTO; SCA: 550600; PA: EDB-99:003713; SN: 98002028034
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 6 Oct 1998
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; SOL-GEL PROCESS; TITANIUM ALLOYS; ION IMPLANTATION; FABRICATION; BONDING; PROSTHESES; SKELETON; ANNEALING; HYDROXIDES; CALCIUM PHOSPHATES

Citation Formats

Nastasi, M.A., Levine, T.E., Mayer, J.W., and Pizziconi, V.B. Processing of hydroxylapatite coatings on titanium alloy bone prostheses. United States: N. p., 1998. Web.
Nastasi, M.A., Levine, T.E., Mayer, J.W., & Pizziconi, V.B. Processing of hydroxylapatite coatings on titanium alloy bone prostheses. United States.
Nastasi, M.A., Levine, T.E., Mayer, J.W., and Pizziconi, V.B. Tue . "Processing of hydroxylapatite coatings on titanium alloy bone prostheses". United States.
@article{osti_675871,
title = {Processing of hydroxylapatite coatings on titanium alloy bone prostheses},
author = {Nastasi, M.A. and Levine, T.E. and Mayer, J.W. and Pizziconi, V.B.},
abstractNote = {Processing of hydroxylapatite sol-gel films on titanium alloy bone prostheses. A method utilizing non-line-of-sight ion beam implantation and/or rapid thermal processing to provide improved bonding of layers of hydroxylapatite to titanium alloy substrates while encouraging bone ingrowth into the hydroxylapatite layers located away from the substrate, is described for the fabrication of prostheses. The first layer of hydroxylapatite is mixed into the substrate by the ions or rapidly thermally annealed, while subsequent layers are heat treated or densified using ion implantation to form layers of decreasing density and larger crystallization, with the outermost layers being suitable for bone ingrowth.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {10}
}