Processing of hydroxylapatite coatings on titanium alloy bone prostheses
Abstract
Processing of hydroxylapatite sol-gel films on titanium alloy bone prostheses. A method utilizing non-line-of-sight ion beam implantation and/or rapid thermal processing to provide improved bonding of layers of hydroxylapatite to titanium alloy substrates while encouraging bone ingrowth into the hydroxylapatite layers located away from the substrate, is described for the fabrication of prostheses. The first layer of hydroxylapatite is mixed into the substrate by the ions or rapidly thermally annealed, while subsequent layers are heat treated or densified using ion implantation to form layers of decreasing density and larger crystallization, with the outermost layers being suitable for bone ingrowth.
- Inventors:
- Issue Date:
- Research Org.:
- University of California
- Sponsoring Org.:
- USDOE, Washington, DC (United States)
- OSTI Identifier:
- 675871
- Patent Number(s):
- 5,817,326
- Application Number:
- PAN: 8-566,339
- Assignee:
- Univ. of California, Los Alamos, NM (United States)
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Resource Relation:
- Other Information: PBD: 6 Oct 1998
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 55 BIOLOGY AND MEDICINE, BASIC STUDIES; SOL-GEL PROCESS; TITANIUM ALLOYS; ION IMPLANTATION; FABRICATION; BONDING; PROSTHESES; SKELETON; ANNEALING; HYDROXIDES; CALCIUM PHOSPHATES
Citation Formats
Nastasi, M A, Levine, T E, Mayer, J W, and Pizziconi, V B. Processing of hydroxylapatite coatings on titanium alloy bone prostheses. United States: N. p., 1998.
Web.
Nastasi, M A, Levine, T E, Mayer, J W, & Pizziconi, V B. Processing of hydroxylapatite coatings on titanium alloy bone prostheses. United States.
Nastasi, M A, Levine, T E, Mayer, J W, and Pizziconi, V B. Tue .
"Processing of hydroxylapatite coatings on titanium alloy bone prostheses". United States.
@article{osti_675871,
title = {Processing of hydroxylapatite coatings on titanium alloy bone prostheses},
author = {Nastasi, M A and Levine, T E and Mayer, J W and Pizziconi, V B},
abstractNote = {Processing of hydroxylapatite sol-gel films on titanium alloy bone prostheses. A method utilizing non-line-of-sight ion beam implantation and/or rapid thermal processing to provide improved bonding of layers of hydroxylapatite to titanium alloy substrates while encouraging bone ingrowth into the hydroxylapatite layers located away from the substrate, is described for the fabrication of prostheses. The first layer of hydroxylapatite is mixed into the substrate by the ions or rapidly thermally annealed, while subsequent layers are heat treated or densified using ion implantation to form layers of decreasing density and larger crystallization, with the outermost layers being suitable for bone ingrowth.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {10}
}
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