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Title: Method for improved selectivity in photo-activation of molecular agents

Abstract

A method for the treatment of a particular volume of plant or animal tissue comprising the steps of treating the plant or animal tissue with at least one photo-active molecular agent, wherein the particular volume of the plant or animal tissue retains at least a portion of the at least one photo-active molecular agent, and then treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of at least one of the at least one photo-active molecular agent retained in the particular volume of the plant or animal tissue, wherein the at least one photo-active molecular agent becomes active in the particular volume of the plant or animal tissue. There is also disclosed a method for the treatment of cancer in plant or animal tissue and a method for producing at least one photo-activated molecular agent in a particular volume of a material. 23 figs.

Inventors:
; ;
Issue Date:
Research Org.:
Lockheed Martin Energy Syst Inc
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
675825
Patent Number(s):
5,829,448
Application Number:
PAN: 8-739,801
Assignee:
Photogen, Inc., Knoxville, TN (United States) PTO; SCA: 550600; PA: EDB-99:003711; SN: 98002027972
DOE Contract Number:  
AC05-84OR21400
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 3 Nov 1998
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; THERAPEUTIC USES; PHOTOCHEMICAL REACTIONS; PLANT TISSUES; ANIMAL TISSUES

Citation Formats

Fisher, W.G., Wachter, E.A., and Dees, H.C. Method for improved selectivity in photo-activation of molecular agents. United States: N. p., 1998. Web.
Fisher, W.G., Wachter, E.A., & Dees, H.C. Method for improved selectivity in photo-activation of molecular agents. United States.
Fisher, W.G., Wachter, E.A., and Dees, H.C. Tue . "Method for improved selectivity in photo-activation of molecular agents". United States.
@article{osti_675825,
title = {Method for improved selectivity in photo-activation of molecular agents},
author = {Fisher, W.G. and Wachter, E.A. and Dees, H.C.},
abstractNote = {A method for the treatment of a particular volume of plant or animal tissue comprising the steps of treating the plant or animal tissue with at least one photo-active molecular agent, wherein the particular volume of the plant or animal tissue retains at least a portion of the at least one photo-active molecular agent, and then treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of at least one of the at least one photo-active molecular agent retained in the particular volume of the plant or animal tissue, wherein the at least one photo-active molecular agent becomes active in the particular volume of the plant or animal tissue. There is also disclosed a method for the treatment of cancer in plant or animal tissue and a method for producing at least one photo-activated molecular agent in a particular volume of a material. 23 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {11}
}