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Title: Ultrasonic characterization of single drops of liquids

Abstract

Ultrasonic characterization of single drops of liquids is disclosed. The present invention includes the use of two closely spaced transducers, or one transducer and a closely spaced reflector plate, to form an interferometer suitable for ultrasonic characterization of droplet-size and smaller samples without the need for a container. The droplet is held between the interferometer elements, whose distance apart may be adjusted, by surface tension. The surfaces of the interferometer elements may be readily cleansed by a stream of solvent followed by purified air when it is desired to change samples. A single drop of liquid is sufficient for high-quality measurement. Examples of samples which may be investigated using the apparatus and method of the present invention include biological specimens (tear drops; blood and other body fluid samples; samples from tumors, tissues, and organs; secretions from tissues and organs; snake and bee venom, etc.) for diagnostic evaluation, samples in forensic investigations, and detection of drugs in small quantities. 5 figs.

Inventors:
Issue Date:
Research Org.:
Univ. of California (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
644439
Patent Number(s):
5739432
Application Number:
PAN: 8-657,709
Assignee:
Univ. of California, Los Alamos, NM (United States)
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 14 Apr 1998
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; ULTRASONIC TESTING; DROPLETS; TRANSDUCERS; INTERFEROMETRY; DIAGNOSTIC TECHNIQUES; CRIME DETECTION; BIOLOGICAL MATERIALS

Citation Formats

Sinha, D N. Ultrasonic characterization of single drops of liquids. United States: N. p., 1998. Web.
Sinha, D N. Ultrasonic characterization of single drops of liquids. United States.
Sinha, D N. Tue . "Ultrasonic characterization of single drops of liquids". United States.
@article{osti_644439,
title = {Ultrasonic characterization of single drops of liquids},
author = {Sinha, D N},
abstractNote = {Ultrasonic characterization of single drops of liquids is disclosed. The present invention includes the use of two closely spaced transducers, or one transducer and a closely spaced reflector plate, to form an interferometer suitable for ultrasonic characterization of droplet-size and smaller samples without the need for a container. The droplet is held between the interferometer elements, whose distance apart may be adjusted, by surface tension. The surfaces of the interferometer elements may be readily cleansed by a stream of solvent followed by purified air when it is desired to change samples. A single drop of liquid is sufficient for high-quality measurement. Examples of samples which may be investigated using the apparatus and method of the present invention include biological specimens (tear drops; blood and other body fluid samples; samples from tumors, tissues, and organs; secretions from tissues and organs; snake and bee venom, etc.) for diagnostic evaluation, samples in forensic investigations, and detection of drugs in small quantities. 5 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {4}
}