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Title: Multiplexed electronically programmable multimode ionization detector for chromatography

Abstract

Method and apparatus for detecting and differentiating organic compounds based on their electron affinity. An electron capture detector cell (ECD) is operated in a plurality of multiplexed electronically programmable operating modes to alter the detector response during a single sampling cycle to acquire multiple simultaneous chromatograms corresponding to each of the different operating modes. The cell is held at a constant subatmospheric pressure while the electron collection bias voltage applied to the cell is modulated electronically to allow acquisition of multiple chromatograms for a single sample elution from a chromatograph representing three distinctly different response modes. A system is provided which automatically controls the programmed application of bias pulses at different intervals and/or amplitudes to switch the detector from an ionization mode to the electron capture mode and various degrees therebetween to provide an improved means of tuning an ECD for multimode detection and improved specificity. 6 figs.

Inventors:
;
Issue Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
OSTI Identifier:
6415321
Patent Number(s):
7196693
Application Number:
ON: DE89009758
Assignee:
Dept. of Energy
Patent Classifications (CPCs):
G - PHYSICS G06 - COMPUTING G06F - ELECTRIC DIGITAL DATA PROCESSING
DOE Contract Number:  
AC05-84OR21400
Resource Type:
Patent
Resource Relation:
Other Information: Portions of this document are illegible in microfiche products
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; ELECTRON-CAPTURE DETECTORS; DESIGN; FLOWSHEETS; GAS CHROMATOGRAPHY; INVENTIONS; ORGANIC COMPOUNDS; CHROMATOGRAPHY; DIAGRAMS; MEASURING INSTRUMENTS; RADIOMETRIC GAGES; SEPARATION PROCESSES; 440300* - Miscellaneous Instruments- (-1989); 400201 - Chemical & Physicochemical Properties

Citation Formats

Wise, M. B., and Buchanan, M. V.. Multiplexed electronically programmable multimode ionization detector for chromatography. United States: N. p., 1988. Web.
Wise, M. B., & Buchanan, M. V.. Multiplexed electronically programmable multimode ionization detector for chromatography. United States.
Wise, M. B., and Buchanan, M. V.. Thu . "Multiplexed electronically programmable multimode ionization detector for chromatography". United States. https://www.osti.gov/servlets/purl/6415321.
@article{osti_6415321,
title = {Multiplexed electronically programmable multimode ionization detector for chromatography},
author = {Wise, M. B. and Buchanan, M. V.},
abstractNote = {Method and apparatus for detecting and differentiating organic compounds based on their electron affinity. An electron capture detector cell (ECD) is operated in a plurality of multiplexed electronically programmable operating modes to alter the detector response during a single sampling cycle to acquire multiple simultaneous chromatograms corresponding to each of the different operating modes. The cell is held at a constant subatmospheric pressure while the electron collection bias voltage applied to the cell is modulated electronically to allow acquisition of multiple chromatograms for a single sample elution from a chromatograph representing three distinctly different response modes. A system is provided which automatically controls the programmed application of bias pulses at different intervals and/or amplitudes to switch the detector from an ionization mode to the electron capture mode and various degrees therebetween to provide an improved means of tuning an ECD for multimode detection and improved specificity. 6 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1988},
month = {5}
}