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Title: Radioiodinated maleimides and use as agents for radiolabeling antibodies

Abstract

A radiopharmaceutical for antibody labeling comprising an iodophenyl maleimide that attaches thiol sites of proteins thereby maintaining bioreactivity largely located at the nitrogen sites.

Inventors:
Issue Date:
Research Org.:
Oak Ridge National Lab., TN (USA)
OSTI Identifier:
6259629
Patent Number(s):
-US-A7177219
Application Number:
ON: DE89011799
Assignee:
Dept. of Energy TIC; ERA-14-029040; EDB-89-078938
DOE Contract Number:  
AC05-84OR21400
Resource Type:
Patent
Resource Relation:
Other Information: Portions of this document are illegible in microfiche products
Country of Publication:
United States
Language:
English
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; 59 BASIC BIOLOGICAL SCIENCES; RADIOPHARMACEUTICALS; LABELLING; ANTIBODIES; DIAGNOSTIC TECHNIQUES; INVENTIONS; IODINATION; PROTEINS; THIOLS; CHEMICAL REACTIONS; DRUGS; HALOGENATION; LABELLED COMPOUNDS; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; 400703* - Radiochemistry & Nuclear Chemistry- Radioisotope Production; 550200 - Biochemistry

Citation Formats

Srivastava, P.C. Radioiodinated maleimides and use as agents for radiolabeling antibodies. United States: N. p., 1988. Web.
Srivastava, P.C. Radioiodinated maleimides and use as agents for radiolabeling antibodies. United States.
Srivastava, P.C. Mon . "Radioiodinated maleimides and use as agents for radiolabeling antibodies". United States.
@article{osti_6259629,
title = {Radioiodinated maleimides and use as agents for radiolabeling antibodies},
author = {Srivastava, P.C.},
abstractNote = {A radiopharmaceutical for antibody labeling comprising an iodophenyl maleimide that attaches thiol sites of proteins thereby maintaining bioreactivity largely located at the nitrogen sites.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1988},
month = {4}
}