Apparatus for eliminating background interference in fluorescence measurements
Abstract
The disclosure is directed to an apparatus for eliminating background interference during fluorescence measurements in a multiple laser flow cytometer. A biological particle stained with fluorescent dyes is excited by a laser. A fluorescence detector detects the fluorescence. The particle scatters light and a gate signal is generated and delayed until the biological particle reaches the next laser. The delayed signal turns on this next laser which excites a different stained component of the same biological particle.
- Inventors:
- Issue Date:
- OSTI Identifier:
- 6111956
- Application Number:
- ON: TI85006515
- Assignee:
- Dept. of Energy
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; CELL FLOW SYSTEMS; BACKGROUND NOISE; FLUORESCENCE SPECTROSCOPY; LASERS; SIGNAL-TO-NOISE RATIO; EMISSION SPECTROSCOPY; NOISE; SPECTROSCOPY; 550300* - Cytology
Citation Formats
Martin, J C, and Jett, J H. Apparatus for eliminating background interference in fluorescence measurements. United States: N. p., 1984.
Web.
Martin, J C, & Jett, J H. Apparatus for eliminating background interference in fluorescence measurements. United States.
Martin, J C, and Jett, J H. Fri .
"Apparatus for eliminating background interference in fluorescence measurements". United States.
@article{osti_6111956,
title = {Apparatus for eliminating background interference in fluorescence measurements},
author = {Martin, J C and Jett, J H},
abstractNote = {The disclosure is directed to an apparatus for eliminating background interference during fluorescence measurements in a multiple laser flow cytometer. A biological particle stained with fluorescent dyes is excited by a laser. A fluorescence detector detects the fluorescence. The particle scatters light and a gate signal is generated and delayed until the biological particle reaches the next laser. The delayed signal turns on this next laser which excites a different stained component of the same biological particle.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1984},
month = {1}
}
Search for the full text at the U.S. Patent and Trademark Office
Note: You will be redirected to the USPTO site, which may require a pop-up blocker to be deactivated to view the patent. If so, you will need to manually turn off your browser's pop-up blocker, typically found within the browser settings. (See DOE Patents FAQs for more information.)
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.