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Title: Palladium-109 labeled anti-melanoma monoclonal antibodies

Abstract

The invention consists of new monoclonal antibodies labelled with Palladium 109, a beta-emitting radionuclide, the method of preparing this material, and its use in the radiotherapy of melanoma. The antibodies are chelate-conjugated and demonstrate a high uptake in melanomas. (ACR)

Inventors:
; ;
Issue Date:
OSTI Identifier:
6110979
Application Number:
ON: TI85006017
Assignee:
Dept. of Energy EDB-85-040047
DOE Contract Number:  
AC02-76CH00016
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MELANOMAS; RADIOTHERAPY; MONOCLONAL ANTIBODIES; CHEMICAL PREPARATION; BIOLOGICAL LOCALIZATION; CHELATES; LABELLED COMPOUNDS; PALLADIUM 109; UPTAKE; ANTIBODIES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; COMPLEXES; DISEASES; EVEN-ODD NUCLEI; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; PALLADIUM ISOTOPES; RADIOISOTOPES; RADIOLOGY; SYNTHESIS; THERAPY; 550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)

Citation Formats

Srivastava, S.C., Fawwaz, R.A., and Ferrone, S. Palladium-109 labeled anti-melanoma monoclonal antibodies. United States: N. p., 1984. Web.
Srivastava, S.C., Fawwaz, R.A., & Ferrone, S. Palladium-109 labeled anti-melanoma monoclonal antibodies. United States.
Srivastava, S.C., Fawwaz, R.A., and Ferrone, S. Mon . "Palladium-109 labeled anti-melanoma monoclonal antibodies". United States.
@article{osti_6110979,
title = {Palladium-109 labeled anti-melanoma monoclonal antibodies},
author = {Srivastava, S.C. and Fawwaz, R.A. and Ferrone, S.},
abstractNote = {The invention consists of new monoclonal antibodies labelled with Palladium 109, a beta-emitting radionuclide, the method of preparing this material, and its use in the radiotherapy of melanoma. The antibodies are chelate-conjugated and demonstrate a high uptake in melanomas. (ACR)},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1984},
month = {4}
}