Palladium-109 labeled anti-melanoma monoclonal antibodies
Abstract
The invention consists of new monoclonal antibodies labelled with Palladium 109, a beta-emitting radionuclide, the method of preparing this material, and its use in the radiotherapy of melanoma. The antibodies are chelate-conjugated and demonstrate a high uptake in melanomas. (ACR)
- Inventors:
- Issue Date:
- OSTI Identifier:
- 6110979
- Application Number:
- ON: TI85006017
- Assignee:
- Dept. of Energy
- DOE Contract Number:
- AC02-76CH00016
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 62 RADIOLOGY AND NUCLEAR MEDICINE; MELANOMAS; RADIOTHERAPY; MONOCLONAL ANTIBODIES; CHEMICAL PREPARATION; BIOLOGICAL LOCALIZATION; CHELATES; LABELLED COMPOUNDS; PALLADIUM 109; UPTAKE; ANTIBODIES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; COMPLEXES; DISEASES; EVEN-ODD NUCLEI; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NUCLEAR MEDICINE; NUCLEI; PALLADIUM ISOTOPES; RADIOISOTOPES; RADIOLOGY; SYNTHESIS; THERAPY; 550604* - Medicine- Unsealed Radionuclides in Therapy- (1980-)
Citation Formats
Srivastava, S C, Fawwaz, R A, and Ferrone, S. Palladium-109 labeled anti-melanoma monoclonal antibodies. United States: N. p., 1984.
Web.
Srivastava, S C, Fawwaz, R A, & Ferrone, S. Palladium-109 labeled anti-melanoma monoclonal antibodies. United States.
Srivastava, S C, Fawwaz, R A, and Ferrone, S. Mon .
"Palladium-109 labeled anti-melanoma monoclonal antibodies". United States.
@article{osti_6110979,
title = {Palladium-109 labeled anti-melanoma monoclonal antibodies},
author = {Srivastava, S C and Fawwaz, R A and Ferrone, S},
abstractNote = {The invention consists of new monoclonal antibodies labelled with Palladium 109, a beta-emitting radionuclide, the method of preparing this material, and its use in the radiotherapy of melanoma. The antibodies are chelate-conjugated and demonstrate a high uptake in melanomas. (ACR)},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Apr 30 00:00:00 EDT 1984},
month = {Mon Apr 30 00:00:00 EDT 1984}
}
