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Title: Laser particle sorter

Abstract

Method and apparatus are provided for sorting particles, such as biological particles. A first laser is used to define an optical path having an intensity gradient which is effective to propel the particles along the path but which is sufficiently weak that the particles are not trapped in an axial direction. A probe laser beam is provided for interrogating the particles to identify predetermined phenotypical characteristics of the particles. A second laser beam is provided to intersect the driving first laser beam, wherein the second laser beam is activated by an output signal indicative of a predetermined characteristic. The second laser beam is switchable between a first intensity and a second intensity, where the first intensity is effective to displace selected particles from the driving laser beam and the second intensity is effective to propel selected particles along the deflection laser beam. The selected particles may then be propelled by the deflection beam to a location effective for further analysis. 2 figs.

Inventors:
;
Issue Date:
Research Org.:
Los Alamos National Lab., NM (USA)
OSTI Identifier:
6079226
Patent Number(s):
-US-A7126156
Application Number:
ON: DE89010956
Assignee:
Dept. of Energy TIC; ERA-14-027043; EDB-89-072806
DOE Contract Number:  
W-7405-ENG-36
Resource Type:
Patent
Resource Relation:
Other Information: Portions of this document are illegible in microfiche products
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION; 59 BASIC BIOLOGICAL SCIENCES; LASERS; PARTICLE DISCRIMINATION; DESIGN; INVENTIONS; PARTICLE IDENTIFICATION; SEPARATION EQUIPMENT; 440300* - Miscellaneous Instruments- (-1989); 550000 - Biomedical Sciences, Basic Studies

Citation Formats

Martin, J.C., and Buican, T.N. Laser particle sorter. United States: N. p., 1987. Web.
Martin, J.C., & Buican, T.N. Laser particle sorter. United States.
Martin, J.C., and Buican, T.N. Mon . "Laser particle sorter". United States.
@article{osti_6079226,
title = {Laser particle sorter},
author = {Martin, J.C. and Buican, T.N.},
abstractNote = {Method and apparatus are provided for sorting particles, such as biological particles. A first laser is used to define an optical path having an intensity gradient which is effective to propel the particles along the path but which is sufficiently weak that the particles are not trapped in an axial direction. A probe laser beam is provided for interrogating the particles to identify predetermined phenotypical characteristics of the particles. A second laser beam is provided to intersect the driving first laser beam, wherein the second laser beam is activated by an output signal indicative of a predetermined characteristic. The second laser beam is switchable between a first intensity and a second intensity, where the first intensity is effective to displace selected particles from the driving laser beam and the second intensity is effective to propel selected particles along the deflection laser beam. The selected particles may then be propelled by the deflection beam to a location effective for further analysis. 2 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1987},
month = {11}
}