High-pressure liquid chromatographic gradient mixer
Abstract
A gradient mixer effects the continuous mixing of any two miscible solvents without excessive decay or dispersion of the resultant isocratic effluent or of a linear or exponential gradient. The two solvents are fed under low or high pressure by means of two high performance liquid chromatographic pumps. The mixer comprises a series of ultra-low dead volume stainless steel tubes and low dead volume chambers. The two solvent streams impinge head-on at high fluxes. This initial nonhomogeneous mixture is then passed through a chamber packed with spirally-wound wires which cause turbulent mixing thereby homogenizing the mixture with minimum band-broadening.
- Inventors:
- Issue Date:
- OSTI Identifier:
- 5708006
- Application Number:
- ON: DE83018103
- Assignee:
- ERA-08-054486; EDB-83-178040
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING; MIXERS; DESIGN; CHROMATOGRAPHY; MICROPROCESSORS; PUMPS; COMPUTERS; ELECTRONIC CIRCUITS; MICROELECTRONIC CIRCUITS; SEPARATION PROCESSES; 420200* - Engineering- Facilities, Equipment, & Techniques
Citation Formats
Daughton, C G, and Sakaji, R H. High-pressure liquid chromatographic gradient mixer. United States: N. p., 1982.
Web.
Daughton, C G, & Sakaji, R H. High-pressure liquid chromatographic gradient mixer. United States.
Daughton, C G, and Sakaji, R H. Wed .
"High-pressure liquid chromatographic gradient mixer". United States.
@article{osti_5708006,
title = {High-pressure liquid chromatographic gradient mixer},
author = {Daughton, C G and Sakaji, R H},
abstractNote = {A gradient mixer effects the continuous mixing of any two miscible solvents without excessive decay or dispersion of the resultant isocratic effluent or of a linear or exponential gradient. The two solvents are fed under low or high pressure by means of two high performance liquid chromatographic pumps. The mixer comprises a series of ultra-low dead volume stainless steel tubes and low dead volume chambers. The two solvent streams impinge head-on at high fluxes. This initial nonhomogeneous mixture is then passed through a chamber packed with spirally-wound wires which cause turbulent mixing thereby homogenizing the mixture with minimum band-broadening.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1982},
month = {9}
}
Search for the full text at the U.S. Patent and Trademark Office
Note: You will be redirected to the USPTO site, which may require a pop-up blocker to be deactivated to view the patent. If so, you will need to manually turn off your browser's pop-up blocker, typically found within the browser settings. (See DOE Patents FAQs for more information.)
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.