skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Biotin compounds for targeting tumors and sites of infection

Abstract

Novel biotin amide analogs that are useful for targeting therapeutic and imaging agents to sites of infection and tumors in vivo are disclosed.

Inventors:
; ; ;
Issue Date:
Research Org.:
Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
570392
Patent Number(s):
5716594
Application Number:
PAN: 8-725,060
Assignee:
JMDE Trust, Newton, MA (United States)
DOE Contract Number:  
FG02-86ER60460
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 10 Feb 1998
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; BIOTIN; AMIDES; NEOPLASMS; INFECTIOUS DISEASES; DRUGS; USES; DIAGNOSIS; THERAPY

Citation Formats

Elmaleh, D R, Fischman, A J, Shoup, T M, and Babich, J W. Biotin compounds for targeting tumors and sites of infection. United States: N. p., 1998. Web.
Elmaleh, D R, Fischman, A J, Shoup, T M, & Babich, J W. Biotin compounds for targeting tumors and sites of infection. United States.
Elmaleh, D R, Fischman, A J, Shoup, T M, and Babich, J W. Tue . "Biotin compounds for targeting tumors and sites of infection". United States.
@article{osti_570392,
title = {Biotin compounds for targeting tumors and sites of infection},
author = {Elmaleh, D R and Fischman, A J and Shoup, T M and Babich, J W},
abstractNote = {Novel biotin amide analogs that are useful for targeting therapeutic and imaging agents to sites of infection and tumors in vivo are disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {2}
}

Works referenced in this record:

Avidin binding of radiolabeled biotin derivatives.
journal, January 1988


An approach to the targeted attachment of peptides and proteins to solid supports.
journal, October 1976


99mTc Labeled Biotin Conjugate in a Tumor“Pretargeting” Approach with Monoclonal Antibodies
journal, November 1992