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Title: Probes labelled with energy transfer coupled dyes

Abstract

Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.

Inventors:
; ;
Issue Date:
Research Org.:
University of California
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
563688
Patent Number(s):
5,688,648
Application Number:
PAN: 8-574,890
Assignee:
Univ. of California, Oakland, CA (United States) PTO; SCA: 550200; PA: EDB-98:016257; SN: 98001896349
DOE Contract Number:  
FG03-91ER61125
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 18 Nov 1997
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; DNA SEQUENCERS; DNA SEQUENCING; DESIGN; FLUORESCENCE; DNA; MOLECULAR BIOLOGY

Citation Formats

Mathies, R.A., Glazer, A., and Ju, J. Probes labelled with energy transfer coupled dyes. United States: N. p., 1997. Web.
Mathies, R.A., Glazer, A., & Ju, J. Probes labelled with energy transfer coupled dyes. United States.
Mathies, R.A., Glazer, A., and Ju, J. Tue . "Probes labelled with energy transfer coupled dyes". United States.
@article{osti_563688,
title = {Probes labelled with energy transfer coupled dyes},
author = {Mathies, R.A. and Glazer, A. and Ju, J.},
abstractNote = {Compositions are provided comprising sets of fluorescent labels carrying pairs of donor and acceptor dye molecules, designed for efficient excitation of the donors at a single wavelength and emission from the acceptor in each of the pairs at different wavelengths. The different molecules having different donor-acceptor pairs can be modified to have substantially the same mobility under separation conditions, by varying the distance between the donor and acceptor in a given pair. Particularly, the fluorescent compositions find use as labels in sequencing nucleic acids. 7 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {11}
}