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Title: Methodology and apparatus for diffuse photon imaging

Abstract

Non-invasive near infrared optical medical imaging devices for both hematoma detection in the brain and early tumor detection in the breast is achieved using image reconstruction which allows a mapping of the position dependent contrast diffusive propagation constants, which are related to the optical absorption coefficient and scattering coefficient in the tissue, at near infrared wavelengths. Spatial resolutions in the range of 5 mm for adult brain sizes and breast sizes can be achieved. The image reconstruction utilizes WKB approximation on most probable diffusion paths which has as lowest order approximation the straight line-of-sight between the plurality of sources and the plurality of detectors. The WKB approximation yields a set of linear equations in which the contrast optical absorption coefficients are the unknowns and for which signals can be generated to produce a pixel map of the contrast optical resolution of the scanned tissue. 58 figs.

Inventors:
; ;
Issue Date:
Research Org.:
University of California
Sponsoring Org.:
Office of Naval Research, Washington, DC (United States); USDOE, Washington, DC (United States)
OSTI Identifier:
563681
Patent Number(s):
5,694,938
Application Number:
PAN: 8-483,329; CNN: Grant N00014-92-J-4004
Assignee:
Univ. of California, Oakland, CA (United States) PTO; SCA: 550600; PA: EDB-98:016271; SN: 98001896323
DOE Contract Number:  
FG03-88ER45378
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 9 Dec 1997
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; IMAGE PROCESSING; PHOTON COMPUTED TOMOGRAPHY; BRAIN; MAMMARY GLANDS; INFRARED RADIATION; PHOTONS; SPATIAL RESOLUTION

Citation Formats

Feng, S.C., Zeng, F., and Zhao, H.L. Methodology and apparatus for diffuse photon imaging. United States: N. p., 1997. Web.
Feng, S.C., Zeng, F., & Zhao, H.L. Methodology and apparatus for diffuse photon imaging. United States.
Feng, S.C., Zeng, F., and Zhao, H.L. Tue . "Methodology and apparatus for diffuse photon imaging". United States.
@article{osti_563681,
title = {Methodology and apparatus for diffuse photon imaging},
author = {Feng, S.C. and Zeng, F. and Zhao, H.L.},
abstractNote = {Non-invasive near infrared optical medical imaging devices for both hematoma detection in the brain and early tumor detection in the breast is achieved using image reconstruction which allows a mapping of the position dependent contrast diffusive propagation constants, which are related to the optical absorption coefficient and scattering coefficient in the tissue, at near infrared wavelengths. Spatial resolutions in the range of 5 mm for adult brain sizes and breast sizes can be achieved. The image reconstruction utilizes WKB approximation on most probable diffusion paths which has as lowest order approximation the straight line-of-sight between the plurality of sources and the plurality of detectors. The WKB approximation yields a set of linear equations in which the contrast optical absorption coefficients are the unknowns and for which signals can be generated to produce a pixel map of the contrast optical resolution of the scanned tissue. 58 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {12}
}