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Title: Nucleotide sequences encoding a thermostable alkaline protease

Abstract

Nucleotide sequences, derived from a thermophilic actinomycete microorganism, which encode a thermostable alkaline protease are disclosed. Also disclosed are variants of the nucleotide sequences which encode a polypeptide having thermostable alkaline proteolytic activity. Recombinant thermostable alkaline protease or recombinant polypeptide may be obtained by culturing in a medium a host cell genetically engineered to contain and express a nucleotide sequence according to the present invention, and recovering the recombinant thermostable alkaline protease or recombinant polypeptide from the culture medium. 3 figs.

Inventors:
;
Issue Date:
Research Org.:
Cornell Univ., Ithaca, NY (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
563671
Patent Number(s):
5705379
Application Number:
PAN: 8-736,361
Assignee:
Cornell Research Foundation, Inc., Ithaca, NY (United States)
DOE Contract Number:  
FG02-84ER13233
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 6 Jan 1998
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; AMINO ACID SEQUENCE; PEPTIDE HYDROLASES; POLYPEPTIDES; GENETIC ENGINEERING; FUNGI

Citation Formats

Wilson, D B, and Lao, G. Nucleotide sequences encoding a thermostable alkaline protease. United States: N. p., 1998. Web.
Wilson, D B, & Lao, G. Nucleotide sequences encoding a thermostable alkaline protease. United States.
Wilson, D B, and Lao, G. Tue . "Nucleotide sequences encoding a thermostable alkaline protease". United States.
@article{osti_563671,
title = {Nucleotide sequences encoding a thermostable alkaline protease},
author = {Wilson, D B and Lao, G},
abstractNote = {Nucleotide sequences, derived from a thermophilic actinomycete microorganism, which encode a thermostable alkaline protease are disclosed. Also disclosed are variants of the nucleotide sequences which encode a polypeptide having thermostable alkaline proteolytic activity. Recombinant thermostable alkaline protease or recombinant polypeptide may be obtained by culturing in a medium a host cell genetically engineered to contain and express a nucleotide sequence according to the present invention, and recovering the recombinant thermostable alkaline protease or recombinant polypeptide from the culture medium. 3 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}