skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Method and apparatus for molecular imaging using x-rays at resonance wavelengths

Abstract

Holographic x-ray images are produced representing the molecular structure of a microscopic object, such as a living cell, by directing a beam of coherent x-rays upon the object to produce scattering of the x-rays by the object, producing interference on a recording medium between the scattered x-rays from the object and unscattered coherent x-rays and thereby producing holograms on the recording surface, and establishing the wavelength of the coherent x-rays to correspond with a molecular resonance of a constituent of such object and thereby greatly improving the contrast, sensitivity and resolution of the holograms as representations of molecular structures involving such constituent. For example, the coherent x-rays may be adjusted to the molecular resonant absorption line of nitrogen at about 401.3 eV to produce holographic images featuring molecular structures involving nitrogen.

Inventors:
OSTI Identifier:
5445988
Application Number:
ON: DE84005934
Assignee:
EDB-84-030607
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Resource Relation:
Other Information: Portions are illegible in microfiche products
Country of Publication:
United States
Language:
English
Subject:
42 ENGINEERING; 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; MOLECULAR STRUCTURE; HOLOGRAPHY; NITROGEN; X-RAY EQUIPMENT; DESIGN; IMAGES; RESONANCE SCATTERING; X RADIATION; ELECTROMAGNETIC RADIATION; ELEMENTS; EQUIPMENT; INELASTIC SCATTERING; IONIZING RADIATIONS; NONMETALS; RADIATIONS; SCATTERING; 420200* - Engineering- Facilities, Equipment, & Techniques; 400201 - Chemical & Physicochemical Properties; 400301 - Organic Chemistry- Chemical & Physicochemical Properties- (-1987)

Citation Formats

Chapline, Jr, G F. Method and apparatus for molecular imaging using x-rays at resonance wavelengths. United States: N. p., Web.
Chapline, Jr, G F. Method and apparatus for molecular imaging using x-rays at resonance wavelengths. United States.
Chapline, Jr, G F. . "Method and apparatus for molecular imaging using x-rays at resonance wavelengths". United States.
@article{osti_5445988,
title = {Method and apparatus for molecular imaging using x-rays at resonance wavelengths},
author = {Chapline, Jr, G F},
abstractNote = {Holographic x-ray images are produced representing the molecular structure of a microscopic object, such as a living cell, by directing a beam of coherent x-rays upon the object to produce scattering of the x-rays by the object, producing interference on a recording medium between the scattered x-rays from the object and unscattered coherent x-rays and thereby producing holograms on the recording surface, and establishing the wavelength of the coherent x-rays to correspond with a molecular resonance of a constituent of such object and thereby greatly improving the contrast, sensitivity and resolution of the holograms as representations of molecular structures involving such constituent. For example, the coherent x-rays may be adjusted to the molecular resonant absorption line of nitrogen at about 401.3 eV to produce holographic images featuring molecular structures involving nitrogen.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {},
month = {}
}