Method and cell lines for the production of monoclonal antibodies to human glycophorin A
Abstract
Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.
- Inventors:
- OSTI Identifier:
- 5433424
- Application Number:
- ON: DE84005984
- Assignee:
- EDB-84-031381
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; BLOOD GROUPS; MONOCLONAL ANTIBODIES; GLUCOPROTEINS; ERYTHROCYTES; HYBRIDOMAS; MAN; MICE; RADIOIMMUNOASSAY; ANIMAL CELLS; ANIMALS; ANTIBODIES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CARBOHYDRATES; ISOTOPE APPLICATIONS; MAMMALS; MATERIALS; ORGANIC COMPOUNDS; PRIMATES; PROTEINS; RADIOASSAY; RODENTS; SACCHARIDES; TRACER TECHNIQUES; VERTEBRATES; 550200* - Biochemistry; 550400 - Genetics; 550900 - Pathology
Citation Formats
Bigbee, W L, Fong, S S.N., Jensen, R H, and Vanderlaan, M. Method and cell lines for the production of monoclonal antibodies to human glycophorin A. United States: N. p.,
Web.
Bigbee, W L, Fong, S S.N., Jensen, R H, & Vanderlaan, M. Method and cell lines for the production of monoclonal antibodies to human glycophorin A. United States.
Bigbee, W L, Fong, S S.N., Jensen, R H, and Vanderlaan, M. .
"Method and cell lines for the production of monoclonal antibodies to human glycophorin A". United States.
@article{osti_5433424,
title = {Method and cell lines for the production of monoclonal antibodies to human glycophorin A},
author = {Bigbee, W L and Fong, S S.N. and Jensen, R H and Vanderlaan, M},
abstractNote = {Cloned mouse hybridoma cell lines have been established which continuously produce antibodies that differentiate between the M and N forms of human glycophorin A. These antibodies have potential application as human blood group reagents, as markers for terminally differentiated erythroid cells and as immunofluorescent labels of somatically variant human erythrocytes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {},
month = {}
}
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