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Title: Thermostable cellulase from a thermomonospora gene

Abstract

The invention relates to a gene isolated from Thermomonospora fusca, wherein the gene encodes a thermostable cellulase. Disclosed is the nucleotide sequence of the T. fusca gene; and nucleic acid molecules comprising the gene, or a fragment of the gene, that can be used to recombinantly express the cellulase or a catalytically active polypeptide thereof, respectively. The isolated and purified recombinant cellulase or catalytically active polypeptide may be used to hydrolyze substrate either by itself; or in combination with other cellulases, with the resultant combination having unexpected hydrolytic activity. 3 figs.

Inventors:
; ;
Issue Date:
Research Org.:
Cornell University
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
541742
Patent Number(s):
5,677,151
Application Number:
PAN: 8-265,429
Assignee:
Cornell Research Foundation, Inc., Ithaca, NY (United States) PTO; SCA: 550200; PA: EDB-97:142342; SN: 97001865602
DOE Contract Number:  
FG02-84ER13233
Resource Type:
Patent
Resource Relation:
Other Information: PBD: 14 Oct 1997
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; CELLULASE; GENES; AMINO ACID SEQUENCE; NUCLEOTIDES; GENE RECOMBINATION; ENZYME ACTIVITY; ENZYMATIC HYDROLYSIS

Citation Formats

Wilson, D.B., Walker, L.P., and Zhang, S. Thermostable cellulase from a thermomonospora gene. United States: N. p., 1997. Web.
Wilson, D.B., Walker, L.P., & Zhang, S. Thermostable cellulase from a thermomonospora gene. United States.
Wilson, D.B., Walker, L.P., and Zhang, S. Tue . "Thermostable cellulase from a thermomonospora gene". United States.
@article{osti_541742,
title = {Thermostable cellulase from a thermomonospora gene},
author = {Wilson, D.B. and Walker, L.P. and Zhang, S.},
abstractNote = {The invention relates to a gene isolated from Thermomonospora fusca, wherein the gene encodes a thermostable cellulase. Disclosed is the nucleotide sequence of the T. fusca gene; and nucleic acid molecules comprising the gene, or a fragment of the gene, that can be used to recombinantly express the cellulase or a catalytically active polypeptide thereof, respectively. The isolated and purified recombinant cellulase or catalytically active polypeptide may be used to hydrolyze substrate either by itself; or in combination with other cellulases, with the resultant combination having unexpected hydrolytic activity. 3 figs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1997},
month = {10}
}